Detection, Characterization, and Clinical Application of Mesenchymal Stem Cells in Periodontal Ligament Tissue.
Detection, Characterization, and Clinical Application of Mesenchymal Stem Cells in Periodontal Ligament Tissue.
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DOI：
10.1155/2018/5450768
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发表时间：
2018
影响因子：
4.3
通讯作者：
Maeda H
中科院分区：
文献类型：
--
作者：
Tomokiyo A;Yoshida S;Hamano S;Hasegawa D;Sugii H;Maeda H
间充质干细胞（MSC）是一种成体干细胞，具有分化成多种细胞类型的潜力，并具有强大的克隆自我更新能力；因此，它们被认为是组织工程中非常有前途的干细胞群。间充质干细胞在包括牙组织在内的各种成人器官中被发现。牙周韧带（PDL）是围绕牙根的高度特化的结缔组织。 PDL 还包含 MSC 群体，许多研究人员已经分离出它们并进行了详细的表征。在此，我们回顾了目前对PDL组织中MSC群体的特征和功能的认识，并讨论了它们在PDL再生中应用的可能性。
Mesenchymal stem cells (MSCs) are a kind of somatic stem cells that exert a potential to differentiate into multiple cell types and undergo robust clonal self-renewal; therefore, they are considered as a highly promising stem cell population for tissue engineering. MSCs are identified in various adult organs including dental tissues. Periodontal ligament (PDL) is a highly specialized connective tissue that surrounds the tooth root. PDL also contains MSC population, and many researchers have isolated them and performed their detailed characterization. Here, we review the current understanding of the features and functions of MSC population in PDL tissues and discuss their possibility for the application of PDL regeneration.
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影响因子：
4.3
作者：
Carnes, DL;Maeder, CL;Graves, DT
通讯作者：
Graves, DT
影响因子：
5.6
作者：
Kukolj, Tamara;Trivanovic, Drenka;Bugarski, Diana
通讯作者：
Bugarski, Diana
影响因子：
6.5
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Erices, A;Conget, P;Minguell, JJ
通讯作者：
Minguell, JJ
影响因子：
5.6
作者：
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通讯作者：
Wang, Songlin
影响因子：
3.6
作者：
Lee, Jeong Seok;An, Seong Yeong;Heo, Jung Sun
通讯作者：
Heo, Jung Sun