Venous and arterial flow quantification are equally accurate and precise with parallel imaging compressed sensing 4D phase contrast MRI.

Venous and arterial flow quantification are equally accurate and precise with parallel imaging compressed sensing 4D phase contrast MRI.
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DOI:
10.1002/jmri.23936
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发表时间:
2013-06
影响因子:
4.4
通讯作者:
Vasanawala, Shreyas S.
Vasanawala, Shreyas S.
中科院分区:
医学2区
文献类型:
--
作者:
Tariq, Umar;Hsiao, Albert;Alley, Marcus;Zhang, Tao;Lustig, Michael;Vasanawala, Shreyas S.

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评价并行成像压缩感知4D相位对比(PICS-4DPC)MRI静脉血流定量在儿童中的精确度和准确度,患者在我们的儿童医院接受心脏MRI。在IRB批准和HIPAA合规性的情况下,22例无分流的连续患者接受了4DPC,作为临床心脏MRI检查的一部分。在上级和下腔静脉、升主动脉和降主动脉以及肺动脉干中获得流量测量。将流向上、下和全身的流量保持作为内部生理控制。采用配对t检验和F检验比较每个位置的动脉和静脉流速,以评估相对准确度和精密度。上(ρ=0.89)、下(ρ=0.96)和全身(ρ=0.97)的动脉和静脉流量测量值密切相关;净主动脉和肺动脉干流速也密切相关(ρ=0.97)。上、下或全身的动脉和静脉血流测量值或精度无显著差异,但在较低的速度编码设置下有提高精度的趋势。使用PICS-4DPC MRI,在适用于动脉血管的速度编码下,静脉血流定量的准确度和精密度与动脉血流定量的准确度和精密度相当。
To evaluate precision and accuracy of parallel-imaging compressed-sensing 4D phase contrast (PICS-4DPC) MRI venous flow quantification in children with patients referred for cardiac MRI at our children’s hospital. With IRB approval and HIPAA compliance, 22 consecutive patients without shunts underwent 4DPC as part of clinical cardiac MRI examinations. Flow measurements were obtained in the superior and inferior vena cava, ascending and descending aorta and the pulmonary trunk. Conservation of flow to the upper, lower and whole body was used as an internal physiologic control. The arterial and venous flow rates at each location were compared with paired t-tests and F-tests to assess relative accuracy and precision. Arterial and venous flow measurements were strongly correlated for the upper (ρ=0.89), lower (ρ=0.96) and whole body (ρ=0.97); net aortic and pulmonary trunk flow rates were also tightly correlated (ρ=0.97). There was no significant difference in the value or precision of arterial and venous flow measurements in upper, lower or whole body, though there was a trend toward improved precision with lower velocity-encoding settings. With PICS-4DPC MRI, the accuracy and precision of venous flow quantification are comparable to that of arterial flow quantification at velocity-encodings appropriate for arterial vessels.
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