An initial exploration of the convergent and ecological validity of the UDS 3.0 neuropsychological battery in Parkinson's Disease.
An initial exploration of the convergent and ecological validity of the UDS 3.0 neuropsychological battery in Parkinson's Disease.
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DOI：
10.1080/13803395.2022.2034753
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发表时间：
2021-11
影响因子：
2.2
通讯作者：
Atri A
中科院分区：
文献类型：
--
作者：
Lea R;Benge JF;Adler CH;Beach TG;Belden CM;Zhang N;Shill HA;Driver-Dunckley E;Mehta SH;Atri A
统一数据集3.0神经心理成套测试（UDS 3 NB）是针对阿尔茨海默病和相关痴呆症研究开发的，可以作为神经退行性疾病认知能力下降的一组常见指标。然而，该电池尚未在帕金森病（PD）患者中进行正式评估。目前的研究提供了初步信息的收敛性和生态有效性的UDS 3 NB在个人与PD。参与者包括来自亚利桑那州衰老和神经退行性疾病研究的75名被诊断为PD的人。独立于认知测量进行的临床痴呆评级将个体鉴定为具有正常认知（n=38）、轻度认知障碍（MCI; n=25）和痴呆（n=12）。比较各组UDS 3 NB测量值，并评估UDS 3 NB测量值、金标准神经心理测量值和被调查者评定的日常生活能力（ADL）活动之间的相关性。在组水平上，UDS 3 NB评分遵循预期模式，PD但无认知诊断的参与者评分较高，痴呆患者评分较低; MCI组的评分介于这两个极端之间。收敛效度建议UDS具体措施（即工艺故事）和措施，如RAVLT之间的适度相关性。UDS 3 NB表现与护理者日常生活能力评分之间的统计学显著相关性表明了生态有效性，其中速度和执行功能测量（Trailmaking A; r=-0.51，p<.01; Trailmaking B; r=-0.51，p<.01）与报告的日常功能关系最密切。研究结果提供了初步支持的收敛性和生态有效性的UDS 3 NB个人与PD。这种电池的影响和未来的发展方向进行了讨论。
The Uniform Data Set 3.0 neuropsychological battery (UDS3NB) is well developed for research with Alzheimer’s disease and related dementias, and may serve as a common set of measures of cognitive decline across neurodegenerative diseases. However, the battery has not been formally assessed in persons with Parkinson’s disease (PD). The current research provides initial information on the convergent and ecological validity of the UDS3NB in individuals with PD. Participants included 75 individuals diagnosed with PD from the Arizona Study of Aging and Neurodegenerative Disorders. Clinical dementia ratings, administered independently from the cognitive measures, identified individuals as having normal cognition (n=38), Mild Cognitive Impairment (MCI; n=25) and dementia (n=12). UDS3NB measures were compared between these groups, and correlations between UDS3NB measures, gold standard neuropsychological measures, and informant rated activities of daily living ability (ADL) were evaluated. At the group-level, UDS3NB scores followed the expected pattern with higher scores in participants with PD but no cognitive diagnosis and lower in those with dementia; scores in the MCI group were between these extremes. Convergent validity was suggested by moderate correlations between UDS specific measures (i.e. Craft story) and measures such as the RAVLT. Ecological validity was suggested by statistically significant correlations between UDS3NB performance and caregiver ratings of ADLs, with speed and executive functioning measures (Trailmaking A; r=−.51, p<.01; Trailmaking B; r=−.51, p<.01) most strongly related to reported daily functioning. Findings provide initial support for the convergent and ecological validity of the UDS3NB in individuals with PD. Implications and future directions for this battery are discussed.
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影响因子：
8.6
作者：
Goldman, Jennifer G.;Holden, Samantha;Ouyang, Bichun;Bernard, Bryan;Goetz, Christopher G.;Stebbins, Glenn T.
通讯作者：
Stebbins, Glenn T.
影响因子：
2.4
作者：
Kiselica, Andrew M.;Webber, Troy A.;Benge, Jared F.
通讯作者：
Benge, Jared F.
DOI：
10.1080/13854046.2020.1837246
发表时间：
2022-08
期刊：
The Clinical neuropsychologist
影响因子：
--
作者：
Benge JF;Artz JD;Kiselica AM
通讯作者：
Kiselica AM
影响因子：
2.1
作者：
Besser L;Kukull W;Knopman DS;Chui H;Galasko D;Weintraub S;Jicha G;Carlsson C;Burns J;Quinn J;Sweet RA;Rascovsky K;Teylan M;Beekly D;Thomas G;Bollenbeck M;Monsell S;Mock C;Zhou XH;Thomas N;Robichaud E;Dean M;Hubbard J;Jacka M;Schwabe-Fry K;Wu J;Phelps C;Morris JC;Neuropsychology Work Group, Directors, and Clinical Core leaders of the National Institute on Aging-funded US Alzheimer’s Disease Centers
通讯作者：
Neuropsychology Work Group, Directors, and Clinical Core leaders of the National Institute on Aging-funded US Alzheimer’s Disease Centers
DOI：
10.1111/j.2517-6161.1995.tb02031.x
发表时间：
1995-01-01
影响因子：
5.8
作者：
BENJAMINI, Y;HOCHBERG, Y
通讯作者：
HOCHBERG, Y