Cooperative Three-View Imaging Optical Coherence Tomography for Intraoperative Vascular Evaluation

Cooperative Three-View Imaging Optical Coherence Tomography for Intraoperative Vascular Evaluation
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用于术中血管评估的协同三视图成像光学相干断层扫描

DOI:
10.3390/app8091551
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发表时间:
2018-09
期刊:
影响因子:
--
通讯作者:
Yong Huang
Yong Huang
中科院分区:
--
文献类型:
--
作者:
Shizhao Peng;Yuanzhen Jiang;Kailin Zhang;Chuanchao Wu;Danni Ai;Jian Yang;Yongtian Wang;Yong Huang

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术中实时光学相干断层扫描(OCT)血管吻合术后成像可以提供重要信息的血管,如通畅性,流速,血栓形态。由于血液的强散射和吸收效应,当直径较大时,常规OCT成像遭受被研究血管的不完整横截面视图的问题。在这项工作中,我们提出了一种新的合作三视图成像光谱域光学相干断层扫描系统术中暴露血管成像。通过定制的样品臂光学设计和相应的机械设计和制造,实现了多个侧面视图(左视图和右视图),可以从三个周向视图方向生成横截面图像,以实现更大的合成视场(FOV)。每个视图的成像深度为6.7mm(空气中),横向扫描范围设计为3mm,通过三视图协同扫描实现了3mm × 3mm的共享合成矩形视场。这种多视图成像方法可以满足外径小于3 mm的血管的周向成像要求。体模管和大鼠血管成像证实了系统FOV性能的提高。我们相信,术中应用这种合作的三成像光学相干断层扫描的客观血管吻合评价可以受益于患者的结果在未来。
Real-time intraoperative optical coherence tomography (OCT) imaging of blood vessels after anastomosis operation can provide important information the vessel, such as patency, flow speed, and thrombosis morphology. Due to the strong scattering and absorption effect of blood, normal OCT imaging suffers from the problem of incomplete cross-sectional view of the vessel under investigation when the diameter is large. In this work, we present a novel cooperative three-view imaging spectral domain optical coherence tomography system for intraoperative exposed vascular imaging. Two more side views (left view and right view) were realized through a customized sample arm optical design and corresponding mechanical design and fabrication, which could generate cross-sectional images from three circumferential view directions to achieve a larger synthetic field of view (FOV). For each view, the imaging depth was 6.7 mm (in air) and the lateral scanning range was designed to be 3 mm. Therefore, a shared synthetic rectangle FOV of 3 mm × 3 mm was achieved through cooperative three view scanning. This multi-view imaging method can meet the circumferential imaging demands of vessels with an outer diameter less than 3 mm. Both phantom tube and rat vessel imaging confirmed the increased system FOV performance. We believe the intraoperative application of this cooperative three-imaging optical coherence tomography for objective vascular anastomosis evaluation can benefit patient outcomes in the future.
DOI: 10.1097/prs.0000000000001124
发表时间: 2015-04
影响因子: 3.6
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期刊: Optics letters
影响因子: 3.6
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DOI: --
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期刊: Lund reports on atomic physics
影响因子: --
作者:
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DOI: 10.1371/journal.pone.0114215
发表时间: 2014
期刊: PloS one
影响因子: 3.7
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