Meteorological factors affect the epidemiology of hemorrhagic fever with renal syndrome via altering the breeding and hantavirus-carrying states of rodents and mites: a 9 years' longitudinal study.
Meteorological factors affect the epidemiology of hemorrhagic fever with renal syndrome via altering the breeding and hantavirus-carrying states of rodents and mites: a 9 years' longitudinal study.
复制标题
气象因素通过改变啮齿动物和螨类的繁殖和汉坦病毒携带状态影响肾综合征出血热的流行病学：一项为期9年的纵向研究
DOI：
10.1038/emi.2017.92
复制
发表时间：
2017-11-29
影响因子：
13.2
通讯作者：
Cao G
中科院分区：
文献类型：
--
作者：
Jiang F;Wang L;Wang S;Zhu L;Dong L;Zhang Z;Hao B;Yang F;Liu W;Deng Y;Zhang Y;Ma Y;Pan B;Han Y;Ren H;Cao G
The incidence of hemorrhagic fever with renal syndrome (HFRS) in Qingdao, China was three times higher than that of the average national level. Here we characterized the epidemiology, ecological determinants and pathogen evolution of HFRS in Qingdao during 2007–2015. In this longitudinal study, a total of 1846 HFRS patients and 41 HFRS-related deaths were reported. HFRS in Qingdao peaked once a year in the fourth quarter. We built a time series generalized additive model, and found that meteorological factors in the previous quarter could accurately predict HFRS occurrence. To explore how meteorological factors influenced the epidemic of HFRS, we analyzed the relationship between meteorological factors and hantavirus-carrying states of the hosts (including rodents and shrews). Comprehensive analysis showed humidity was correlated to high host densities in the third quarter and high hantavirus-carrying rates of animal hosts in the third to fourth quarters, which might contribute to HFRS peak in the fourth quarter. We further compared the L segments of hantaviruses from HFRS patients, animal hosts and ectoparasites. Phylogenetic analysis showed that hantaviruses in gamasid and trombiculid mites were the same as those from the hosts. This indicated mites also contributed to the transmission of hantavirus. Furthermore, Hantaan virus from HFRS patients, hosts and mites in Qingdao formed a distinct phylogenetic cluster. A new clade of Seoul virus was also identified in the hosts. Overall, meteorological factors increase HFRS incidence possibly via facilitating hosts’ reproduction and consequent mite-mediated hantavirus transmission. New hantavirus subtypes evolved in Qingdao represent new challenges of fighting against HFRS.
登录
查看更多内容
韩国共和国自然界中的遗传多样性和汉塔病毒三方RNA基因组的遗传多样性和重新分类。
影响因子：
3.8
作者：
Kim JA;Kim WK;No JS;Lee SH;Lee SY;Kim JH;Kho JH;Lee D;Song DH;Gu SH;Jeong ST;Park MS;Kim HC;Klein TA;Song JW
通讯作者：
Song JW
从韩国3个省份的小型哺乳动物收集的幼虫小螨。
DOI：
10.3347/kjp.2014.52.2.225
发表时间：
2014-04
期刊：
The Korean journal of parasitology
影响因子：
--
作者：
Lee IY;Song HJ;Choi YJ;Shin SH;Choi MK;Kwon SH;Shin EH;Park C;Kim HC;Klein TA;Park KH;Jang WJ
通讯作者：
Jang WJ
影响因子：
3.2
作者：
Lin, Hualiang;Zhang, Zhentang;Liu, Qiyong
通讯作者：
Liu, Qiyong
中国淄博市肾综合征出血热，2006-2014年
影响因子：
11.8
作者：
Wang, Ling;Wang, Tao;Yu, Xue-Jie
通讯作者：
Yu, Xue-Jie
影响因子：
3.7
作者：
Zhang S;Wang S;Yin W;Liang M;Li J;Zhang Q;Feng Z;Li D
通讯作者：
Li D