Premenstrual symptoms as a marker of ovarian hormone sensitivity in eating disorders.
Premenstrual symptoms as a marker of ovarian hormone sensitivity in eating disorders.
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DOI：
10.1002/eat.23213
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发表时间：
2020-02
期刊：
影响因子：
--
通讯作者：
Baker JH
中科院分区：
文献类型：
--
作者：
Hardin SL;Thornton LM;Munn-Chernoff MA;Baker JH
研究表明卵巢激素和饮食病理学之间存在联系，这表明一些患有饮食失调的女性可能对卵巢激素敏感。使用经前症状（PMS）作为卵巢激素敏感性的间接测量，我们调查了11个PMS领域与四个核心饮食失调症状之间的关联：身体不满，暴饮暴食，净化和限制。参与者是完成在线调查的年轻成年女性（N = 455）。经前综合征的评估使用每日记录的严重程度的问题和饮食病理与饮食病理症状清单。计算PMS领域和饮食失调症状之间的Pearson相关性，然后进行逐步回归，为每种饮食失调症状创建更精确的模型，包括相关协变量。大多数进食障碍症状与经前综合征之间存在显著相关性（r = 0.13 - 0.37; p <0.01）。后向回归显示，每个症状的PMS领域的预测显着。最终模型捕获了每种进食障碍症状的小到中等量的方差（R2 = 0.06-0.25）。经历身体和心理经前综合症的女性可能有饮食失调症状的风险;经前综合症可能是饮食失调风险女性卵巢激素敏感性的标志。未来的研究应该解决这种关联的机制。
Research indicates a link between ovarian hormones and eating pathology, suggesting that some women with an eating disorder may be ovarian hormone sensitive. Using premenstrual symptoms (PMS) as an indirect measure of ovarian hormone sensitivity, we investigated the association between 11 PMS domains and four core eating disorder symptoms: body dissatisfaction, binge eating, purging, and restriction. Participants were young adult women (N = 455) who completed an online survey. PMS were assessed using the Daily Record of Severity of Problems and eating pathology with the Eating Pathology Symptoms Inventory. Pearson correlations were calculated between PMS domains and eating disorder symptoms followed by a stepwise regression to create a more refined model for each eating disorder symptom, including relevant covariates. Significant correlations between a majority of eating disorder symptoms and PMS emerged (r's = .13–.37; p < .01). Backward regression revealed significant PMS domain predictors for each symptom. The final models captured a small-to-moderate amount of variance for each eating disorder symptom (R2 = 0.06–0.25). Women who experience physical and psychological PMS may be at risk for eating disorder symptoms; PMS could be a marker of ovarian hormone sensitivity in women at risk for an eating disorder. Future studies should address mechanisms underlying this association.
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