Genetic and environmental influences on motor function: a magnetoencephalographic study of twins.
Genetic and environmental influences on motor function: a magnetoencephalographic study of twins.
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DOI：
10.3389/fnhum.2014.00455
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发表时间：
2014
影响因子：
2.9
通讯作者：
Yorifuji S
中科院分区：
文献类型：
--
作者：
Araki T;Hirata M;Sugata H;Yanagisawa T;Onishi M;Watanabe Y;Omura K;Honda C;Hayakawa K;Yorifuji S
为了研究遗传和环境对大脑运动功能的影响，我们确定了中年和老年同卵双胞胎（MZ）运动相关皮层区域（MRCF）的异同。当同卵双胞胎被指示重复抬起右手食指时，使用 160 通道脑磁图系统测量 MRCF。我们比较了 16 名同卵双胞胎和 16 对遗传无关的双胞胎之间的运动诱发场 1 (MEF1) 的潜伏期、振幅、偶极位置和偶极强度。同卵双胞胎之间潜伏期和偶极位置的差异显着小于年龄不相关的双胞胎之间的差异。然而，振幅和偶极子强度没有显着差异。这些结果表明MEF1的潜伏期和偶极子位置在生命早期由遗传和早期常见环境因素决定，而振幅和偶极子强度则受到长期环境因素的影响。更好地了解影响大脑运动功能的遗传和环境因素可能有助于评估和改善个体运动功能。
To investigate the effect of genetic and environmental influences on cerebral motor function, we determined similarities and differences of movement-related cortical fields (MRCFs) in middle-aged and elderly monozygotic (MZ) twins. MRCFs were measured using a 160-channel magnetoencephalogram system when MZ twins were instructed to repeat lifting of the right index finger. We compared latency, amplitude, dipole location, and dipole intensity of movement-evoked field 1 (MEF1) between 16 MZ twins and 16 pairs of genetically unrelated pairs. Differences in latency and dipole location between MZ twins were significantly less than those between unrelated age-matched pairs. However, amplitude and dipole intensity were not significantly different. These results suggest that the latency and dipole location of MEF1 are determined early in life by genetic and early common environmental factors, whereas amplitude and dipole intensity are influenced by long-term environmental factors. Improved understanding of genetic and environmental factors that influence cerebral motor function may contribute to evaluation and improvement for individual motor function.
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影响因子：
5.7
作者：
Fischl, B;Sereno, MI;Dale, AM
通讯作者：
Dale, AM
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Sereno, MI
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