One stomach, two subtypes of carcinoma-the differences between distal and proximal gastric cancer.

One stomach, two subtypes of carcinoma-the differences between distal and proximal gastric cancer.
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一个胃,两种癌亚型——远端胃癌和近端胃癌的区别

DOI:
10.1093/gastro/goab050
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发表时间:
2021-12
影响因子:
3.6
通讯作者:
Huang C
Huang C
中科院分区:
医学3区
文献类型:
--
作者:
Zhang Y;Zhang PS;Rong ZY;Huang C

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胃癌是消化道最常见的恶性肿瘤之一,严重威胁人类健康。近10年来,人们根据肿瘤的发生部位将其分为近端型和远端型两大类,并对其病理特征和预后进行了研究。本文就近端胃癌与远端胃癌在流行病学、病因学、细胞来源、病理特征、基因表达、分子标志物、临床表现、治疗、预后及预防等方面的差异进行综述,为临床诊治提供指导和依据。
Gastric cancer (GC) is one of the most common malignant tumors of the digestive tract, posing a significant risk to human health. Over the past 10 years, the pathological characteristics and the prognosis of GC have been determined based on the locations of the tumors that were then classified into two types—proximal and distal GC. This review focuses on the differences in epidemiology, etiology, cell source, pathological characteristics, gene expression, molecular markers, manifestations, treatment, prognosis, and prevention between proximal and distal GC to provide guidance and a basis for clinical diagnosis and treatment.
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