Design rules for pumping and metering of highly viscous fluids in microfluidics.
Design rules for pumping and metering of highly viscous fluids in microfluidics.
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DOI：
10.1039/c0lc00035c
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发表时间：
2010-11-21
期刊：
影响因子：
6.1
通讯作者：
Kenis PJ
中科院分区：
文献类型：
--
作者：
Perry SL;Higdon JJ;Kenis PJ
由于其在微通道中的高流动阻力，在微流体中使用比水粘稠得多的流体受到限制。本文报告了变形微流体通道中高粘性流体流动的理论处理，特别是瞬态效应，并讨论了这些效应对设计适用于高粘性流体的适当微流体装置的影响。我们将描述变形通道中的流动的理论与设计方程结合起来，既适用于稳态流动，也适用于与通道的初始变形和最终松弛相关的瞬态周期。该分析的结果使我们能够描述这些系统，并评估不同参数对各种变形和/或瞬态效应的重要性。为了举例说明它们的实用性，我们将这些设计规则应用于两种应用：(i) 泵送高粘度流体用于纳升规模的混合应用；(ii) 微流体中流体的精确计量。
The use of fluids that are significantly more viscous than water in microfluidics has been limited due to their high resistance to flow in microscale channels. This paper reports a theoretical treatment for the flow of highly viscous fluids in deforming microfluidic channels, particularly with respect to transient effects, and discusses the implications of these effects on the design of appropriate microfluidic devices for highly viscous fluids. We couple theory describing flow in a deforming channel with design equations, both for steady-state flows and for the transient periods associated with the initial deformation and final relaxation of a channel. The results of this analysis allow us to describe these systems and also to assess the significance of different parameters on various deformation and/or transient effects. To exemplify their utility, we apply these design rules to two applications: (i) pumping highly viscous fluids for a nanolitre scale mixing application and (ii) precise metering of fluids in microfluidics.
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影响因子：
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