Physiological Recordings of the Cerebellum in Movement Disorders.

Physiological Recordings of the Cerebellum in Movement Disorders.
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DOI:
10.1007/s12311-022-01473-6
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发表时间:
2023-10
期刊:
Cerebellum (London, England)
影响因子:
--
通讯作者:
--
中科院分区:
其他
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小脑在运动障碍中起重要作用,特别是在共济失调、震颤和肌张力障碍的症状中。了解小脑的生理信号有助于深入了解这些运动障碍的病理生理学,并有望推动治疗的发展。脑电、脑磁图等非侵入性技术可以记录毫秒级的高时间分辨率神经信号,特别适合于小脑生理的研究。这些技术最近已被用于研究健康受试者以及运动障碍患者的小脑生理学。在目前的审查中,我们专注于目前的理解小脑生理学使用这些技术来研究运动障碍。
The cerebellum plays an important role in movement disorders, specifically in symptoms of ataxia, tremor, and dystonia. Understanding the physiological signals of the cerebellum contributes to insights into the pathophysiology of these movement disorders and holds promise in advancing therapeutic development. Non-invasive techniques such as electroencephalogram and magnetoencephalogram can record neural signals with high temporal resolution at the millisecond level, which is uniquely suitable to interrogate cerebellar physiology. These techniques have recently been implemented to study cerebellar physiology in healthy subjects as well as individuals with movement disorders. In the present review, we focus on the current understanding of cerebellar physiology using these techniques to study movement disorders.
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