Modeling the spatial spread of infectious diseases: the GLobal Epidemic and Mobility computational model.

Modeling the spatial spread of infectious diseases: the GLobal Epidemic and Mobility computational model.
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DOI:
10.1016/j.jocs.2010.07.002
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发表时间:
2010-08-01
影响因子:
3.3
通讯作者:
Vespignani, Alessandro
Vespignani, Alessandro
中科院分区:
计算机科学3区
文献类型:
--
作者:
Balcan, Duygu;Goncalves, Bruno;Hu, Hao;Ramasco, Jose J.;Colizza, Vittoria;Vespignani, Alessandro

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在这里,我们提出了全球流行病和流动性(GLEaM)模型,该模型将社会人口和人口流动性数据集成在一个空间结构化的随机疾病方法中,以模拟流行病在全球范围内的传播。我们讨论了该模型的灵活结构,该模型对不同疾病结构和当地干预政策的纳入是开放的。这使得GLEaM适用于全球流行病传播的时空模式的计算建模和预测,历史流行病的理解,人类流动性在塑造全球流行病中的作用的评估,以及缓解和遏制情景的分析。
Here we present the Global Epidemic and Mobility (GLEaM) model that integrates sociodemographic and population mobility data in a spatially structured stochastic disease approach to simulate the spread of epidemics at the worldwide scale. We discuss the flexible structure of the model that is open to the inclusion of different disease structures and local intervention policies. This makes GLEaM suitable for the computational modeling and anticipation of the spatio-temporal patterns of global epidemic spreading, the understanding of historical epidemics, the assessment of the role of human mobility in shaping global epidemics, and the analysis of mitigation and containment scenarios.
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