Retrospective study of dilated cardiomyopathy in dogs.
Retrospective study of dilated cardiomyopathy in dogs.
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DOI：
10.1111/jvim.15972
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发表时间：
2021-01
影响因子：
2.6
通讯作者：
Yang VK
中科院分区：
文献类型：
--
作者：
Freid KJ;Freeman LM;Rush JE;Cunningham SM;Davis MS;Karlin ET;Yang VK
美国食品和药物管理局正在调查狗和猫可能与饮食相关的扩张型心肌病（DCM）。回顾性审查 DCM 病例的信号、饮食信息、超声心动图变化和生存情况。客户拥有的狗（n = 71）。审查了2014年1月1日至2018年9月30日期间诊断患有DCM的狗的医疗记录。狗被分为“传统”或“非传统”饮食类别，以及诊断后是否改变饮食。对于吃非传统饮食的狗来说，与那些没有改变饮食的狗相比，那些改变饮食的狗的标准化收缩期左心室内部尺寸 (P = .03) 和左心房:主动脉比率 (P < .001) 下降幅度更大。与食用未改变饮食的非传统饮食的患有 DCM 的狗（中位生存期，215 天；范围，1-852 天；P = .002）相比，食用非传统饮食并改变饮食的 DCM 狗的生存时间明显更长（中位生存期，337 天；范围，9-1307 天）。患有扩张型心肌病（DCM）的狗在改变饮食后，接受非传统饮食，其心脏功能会得到改善，但还需要更多的研究来检验饮食与扩张型心肌病（DCM）之间可能存在的关联。
The United States Food and Drug Administration is investigating possible diet‐associated dilated cardiomyopathy (DCM) in dogs and cats. To retrospectively review DCM cases for signalment, diet information, echocardiographic changes, and survival. Client‐owned dogs (n = 71). Medical records of dogs diagnosed with DCM between January 1, 2014 and September 30, 2018 were reviewed. Dogs were grouped into “traditional” or “nontraditional” diet categories and whether or not diet was changed after diagnosis. For dogs eating nontraditional diets, those that had their diets changed had a larger percentage decrease in normalized systolic left ventricular internal dimension (P = .03) and left atrial:aorta ratio (P < .001) compared to those that did not have their diets changed. Survival time was significantly longer for dogs with DCM eating nontraditional diets that had their diets changed (median survival, 337 days; range, 9‐1307 days) compared to dogs eating nontraditional diets that did not have their diets changed (median survival, 215 days; range, 1‐852 days; P = .002). Dogs with DCM eating nontraditional diets can experience improvement in cardiac function after diet change but additional research is needed to examine possible associations between diet and DCM.
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影响因子：
1.6
作者：
Martin, M. W. S.;Johnson, M. J. Stafford;Celona, B.
通讯作者：
Celona, B.
影响因子：
1.6
作者：
Martin, M. W. S.;Johnson, M. J. Stafford;King, J. N.
通讯作者：
King, J. N.
影响因子：
2.2
作者：
Vollmar, C.;Vollmar, A.;Kohn, B.
通讯作者：
Kohn, B.
影响因子：
3.7
作者：
Kaplan, Joanna L.;Stern, Joshua A.;Ontiveros, Eric
通讯作者：
Ontiveros, Eric
影响因子：
2.6
作者：
Oyama, M. A.;Chittur, S. V.;Reynolds, C. A.
通讯作者：
Reynolds, C. A.