Advantages of a Photodiode Detector Endoscopy System in Fluorescence-Guided Percutaneous Liver Biopsies.
Advantages of a Photodiode Detector Endoscopy System in Fluorescence-Guided Percutaneous Liver Biopsies.
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作者：
Marcos-Vidal A;Heidari P;Xu S;Wood BJ;Mahmood U
当结合肿瘤中积累的吲哚菁绿色（ICG）荧光的光学检测时，图像引导的肝活检可以提高其成功率。先前的工作使用耦合到薄管道镜的相机来捕获和量化手术过程中荧光发射的图像;然而，光散射阻止了清晰图像的形成，并且弱荧光肿瘤的时间响应非常低。相反，用光电二极管检测器代替相机在更紧凑和更轻的设备中显示出改进的时间分辨率。这项工作提出了新的设计，在两种检测技术之间的比较研究，包括评估的时间响应和灵敏度的背景荧光的存在。
Image-guided liver biopsies can improve their success rate when combined with the optical detection of Indocyanine Green (ICG) fluorescence accumulated in tumors. Previous works used a camera coupled to a thin borescope to capture and quantify images from fluorescence emission during procedures; however, light-scattering prevented the formation of sharp images, and the time response for weakly fluorescent tumors was very low. Instead, replacing the camera with a photodiode detector shows an improved temporal resolution in a more compact and lighter device. This work presents the new design in a comparative study between both detection technologies, including an assessment of the temporal response and sensitivity to the presence of background fluorescence.
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