Nickel-catalyzed borylation of halides and pseudohalides with tetrahydroxydiboron [B2(OH)4].
Nickel-catalyzed borylation of halides and pseudohalides with tetrahydroxydiboron [B2(OH)4].
复制标题
DOI：
10.1021/jo401104y
复制
发表时间：
2013-07-05
期刊：
影响因子：
--
通讯作者：
García-García C
中科院分区：
文献类型：
--
作者：
Molander GA;Cavalcanti LN;García-García C
Arylboronic acids are gaining increased importance as reagents and target structures in a variety of useful applications. Recently, the palladium-catalyzed synthesis of arylboronic acids employing the atom economical tetrahydroxydiboron (BBA) reagent has been reported. The high cost associated with palladium, combined with several limitations of both palladium and copper-catalyzed processes, prompted us to develop an alternative method. Thus, the nickel-catalyzed borylation of aryl and heteroaryl halides and pseudo-halides using tetrahydroxydiboron (BBA) has been formulated. The reaction proved to be widely functional group tolerant and applicable to a number of heterocyclic systems. To the best of our knowledge, the examples presented here represent the only effective Ni-catalyzed Miyaura borylations conducted at room temperature.
登录
查看更多内容
影响因子：
15
作者：
Knapp DM;Gillis EP;Burke MD
通讯作者：
Burke MD
影响因子：
56.9
作者：
Chen, HY;Schlecht, S;Hartwig, JF
通讯作者：
Hartwig, JF
影响因子：
3.6
作者：
Hartsel, Joshua A.;Craft, Derek T.;Carlier, Paul R.
通讯作者：
Carlier, Paul R.
影响因子：
1.8
作者：
Ma, DW;Wu, QQ
通讯作者：
Wu, QQ
影响因子：
15
作者：
Deng, HB;Jung, JK;Hoveyda, AH
通讯作者：
Hoveyda, AH