The neuronal organization of a unique cerebellar specialization: the valvula cerebelli of a mormyrid fish.
The neuronal organization of a unique cerebellar specialization: the valvula cerebelli of a mormyrid fish.
复制标题
DOI：
10.1002/cne.21735
复制
发表时间：
2008-08-10
期刊：
影响因子：
--
通讯作者：
Han VZ
中科院分区：
文献类型：
--
作者：
Shi Z;Zhang Y;Meek J;Qiao J;Han VZ
小脑远端瓣膜是小脑小脑最突出的部分。它被组织成神经节和分子层的脊，方向垂直于颗粒层。我们结合了细胞内记录和标记技术来揭示切片制剂中瓣膜脊的细胞形态。我们还在切片和完整动物中局部喷射示踪剂，以检查其输入纤维。浦肯野细胞的栅栏树突和细轴突乔木在脊的水平面上定向。基底传出细胞和大中央细胞的树突局限于分子层，但不是平面的。基底传出细胞轴突很厚，并加入离开小脑的基底束。大的中央细胞轴突也很厚，并且在横向平面上穿越很长的距离，在神经节层中具有局部侧络。垂直细胞和小中央细胞也有粗轴突和局部侧络。高尔基细胞的树突局限于分子层，但其轴突乔木要么局限于颗粒层，要么在颗粒层和神经节层中增殖。深层星状细胞的树突分布在分子层，神经节层有细小的轴突乔木。颗粒细胞轴突作为平行纤维进入分子层，不分叉。攀爬纤维在水平面上延伸，仅终止于神经节层。我们的结果证实并扩展了之前的研究，并提出了小脑绦虫瓣膜回路的新概念。
The distal valvula cerebelli is the most prominent part of the mormyrid cerebellum. It is organized in ridges of ganglionic and molecular layers, oriented perpendicular to the granular layer. We have combined intracellular recording and labelling techniques to reveal the cellular morphology of the valvula ridges in slice preparations. We have also locally ejected tracer in slices and in intact animals to examine its input fibers. The palisade dendrites and fine axon arbors of Purkinje cells are oriented in the horizontal plane of the ridge. The dendrites of basal efferent cells and large central cells are confined to the molecular layer, but are not planer. Basal efferent cell axons are thick, and join the basal bundle leaving the cerebellum. Large central cell axons are also thick, and traverse long distances in the transverse plane, with local collaterals in the ganglionic layer. Vertical cells and small central cells also have thick axons with local collaterals. The dendrites of Golgi cells are confined to the molecular layer, but their axon arbors are either confined to the granular layer or proliferate in both the granular and ganglionic layers. Dendrites of deep stellate cells are distributed in the molecular layer, with fine axon arbors in the ganglionic layer. Granule cell axons enter the molecular layer as parallel fibers without bifurcating. Climbing fibers run in the horizontal plane and terminate exclusively in the ganglionic layer. Our results confirm and extend previous studies and suggest a new concept of the circuitry of the mormyrid valvula cerebelli.
登录
查看更多内容
影响因子：
64.8
作者：
Bell, CC;Han, VZ;Grant, K
通讯作者：
Grant, K
影响因子：
16.2
作者：
Han, VZ;Grant, K;Bell, CC
通讯作者：
Bell, CC
影响因子：
2.5
作者：
BELL, CC;GRANT, K;SERRIER, J
通讯作者：
SERRIER, J
影响因子：
2.5
作者：
Campbell, Holly R.;Meek, Johannes;Bell, Curtis C.
通讯作者：
Bell, Curtis C.
影响因子：
2.5
作者：
BISHOP, GA;ODONOGHUE, DL
通讯作者：
ODONOGHUE, DL