Schistosoma mansoni.

Schistosoma mansoni.
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曼氏血吸虫

DOI:
10.1016/j.pt.2020.06.003
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发表时间:
2021-03
影响因子:
9.6
通讯作者:
Enabulele EE
Enabulele EE
中科院分区:
医学1区
文献类型:
--
作者:
Anderson TJC;Enabulele EE

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曼氏血吸虫是肠道血吸虫病的病原体,每年感染约5400万人,造成显著的死亡率和发病率。这种寄生吸虫在撒哈拉以南非洲和中东地区流行,并在跨大西洋奴隶贸易期间在南美洲殖民。寄生虫在五种不同的身体计划之间过渡,在蜗牛宿主中无性繁殖,在脊椎动物宿主中有性繁殖,以及能动的自由生活阶段。接触含有受感染双脐螺属的水的传播结果。蜗牛学龄儿童的感染率和感染强度最高:减少与水接触和获得性免疫都减少了成人的感染。人类宿主的病理学是由在肝脏和肠道中捕获的卵周围形成的肉芽肿引起的。目前还没有有效的疫苗可用:用吡喹酮治疗受感染的病人是控制工作的主要手段。
Schistosoma mansoni is the causative agent of intestinal schistosomiasis and infects ~54 million people annually, causing significant mortality and morbidity. This parasitic trematode is endemic in sub-Saharan Africa and the Middle East, and colonized South America during the transatlantic slave trade. Parasites transition between five distinctive body plans, with asexual proliferation in the snail host and sexual proliferation in the vertebrate host, and motile free-living stages. Transmission results from contact with water containing infected Biomphalaria spp. snails. Infection prevalence and intensity peaks in school age children: both reduced water contact and acquired immunity reduces infection in adults. Pathology to the human host results from granulomas that form around eggs trapped in the liver and gut. These is no effective vaccine available: treatment of infected patients with praziquantel is the mainstay of control efforts.
DOI: 10.1016/j.pt.2018.08.001
发表时间: 2018-11
影响因子: 9.6
作者:
Anderson TJC;LoVerde PT;Le Clec'h W;Chevalier FD
通讯作者: Chevalier FD
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DOI: 10.1007/s11248-013-9779-3
发表时间: 2014-06-01
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通过循环的阴极抗原尿液测定法或Kato-katz粪便测定法确定的曼氏菌患病率和感染强度的比较:系统评价。
DOI: 10.4269/ajtmh.15-0725
发表时间: 2016-03
期刊: The American journal of tropical medicine and hygiene
影响因子: --
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Kittur N;Castleman JD;Campbell CH;King CH;Colley DG
通讯作者: Colley DG