Effects of alcohol on the endocrine system.
Effects of alcohol on the endocrine system.
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DOI：
10.1016/j.ecl.2013.05.008
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发表时间：
2013-09
影响因子：
4.5
通讯作者：
Sarkar, Dipak K.
中科院分区：
文献类型：
--
作者：
Rachdaoui, Nadia;Sarkar, Dipak K.
内分泌系统确保身体不同器官之间的适当沟通，以维持恒定的内部环境。内分泌系统在使身体能够应对和适当地应对内外环境的变化，如对压力和伤害的反应方面，也起着至关重要的作用。内分泌系统维持身体动态平衡的这些功能是通过它与神经系统、免疫系统和身体的昼夜节律机制的沟通而得到帮助的。长期大量饮酒会扰乱神经、内分泌和免疫系统之间的通讯，引起荷尔蒙紊乱，在生理和行为层面上造成深远而严重的后果。这些由酒精引起的激素失调会影响整个身体，并可能导致各种疾病，如应激异常、生殖缺陷、身体生长缺陷、甲状腺问题、免疫功能障碍、癌症、骨病以及心理和行为障碍。这篇综述总结了人类和动物研究的结果，这些研究为酒精滥用对内分泌系统的各种影响提供了一致的证据。
The endocrine system ensures a proper communication between various organs of the body to maintain a constant internal environment. The endocrine system also plays an essential role in enabling the body to respond and appropriately cope with changes in the internal or external environments, such as respond to stress and injury. These functions of the endocrine system to maintain body homeostasis are aided by its communication with the nervous system, immune system and body’s circadian mechanism. Chronic consumption of a large amount of alcohol disrupts the communication between nervous, endocrine and immune system and causes hormonal disturbances that lead to profound and serious consequences at physiological and behavioral levels. These alcohol-induced hormonal dysregulations affect the entire body and can result in various disorders such as stress abnormalities, reproductive deficits, body growth defect, thyroid problems, immune dysfunction, cancers, bone disease and psychological and behavioral disorders. This review summarizes the findings from human and animal studies that provide consistent evidence on the various effects of alcohol abuse on the endocrine system.
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影响因子：
8.2
作者：
Bonnet, F.;Disse, E.;Balkau, B.
通讯作者：
Balkau, B.
影响因子：
3.7
作者：
Blomeyer D;Buchmann AF;Lascorz J;Zimmermann US;Esser G;Desrivieres S;Schmidt MH;Banaschewski T;Schumann G;Laucht M
通讯作者：
Laucht M
影响因子：
2.3
作者：
Calogero, AE
通讯作者：
Calogero, AE
影响因子：
4.7
作者：
Chen, CP;Kuhn, P;Sarkar, DK
通讯作者：
Sarkar, DK
影响因子：
4.4
作者：
Corbin, William R.;Farmer, Nicole M.;Nolen-Hoekesma, Susan
通讯作者：
Nolen-Hoekesma, Susan