Optimizing Non-Antibiotic Treatments for Patients with Acne: A Review.

Optimizing Non-Antibiotic Treatments for Patients with Acne: A Review.
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DOI:
10.1007/s13555-016-0138-1
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发表时间:
2016-12
影响因子:
3.4
通讯作者:
Elewski, Boni E.
Elewski, Boni E.
中科院分区:
医学3区
文献类型:
--
作者:
Canavan, Theresa N.;Chen, Edward;Elewski, Boni E.

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痤疮是一种非常常见的非感染性皮肤病,经常在皮肤科治疗。由于痤疮通常是慢性的,可能持续多年,因此通常需要安全有效的长期维持治疗。鉴于越来越多的耐药细菌的频率和这种趋势的后果的严重性,皮肤科医生在治疗痤疮时应最大限度地使用非抗菌治疗。在这篇文献综述中,我们提供了关于痤疮非抗菌治疗的有效性和适当使用的数据。存在多种局部和口服治疗选择,可以根据患者的严重程度和治疗反应以逐步的方式使用。非抗菌治疗在控制痤疮方面非常有效,特别是用作维持治疗时。虽然抗生素在痤疮治疗中发挥作用,但它们不应作为单一疗法使用,并且不鼓励使用抗生素的冗长疗程。
Acne is a very common non-infectious skin condition that is frequently treated in dermatological practices. Because acne is often chronic and may persist for years, safe and effective long-term maintenance therapy is often required. Given the increasing frequency of antibiotic-resistant bacteria and the gravity of the consequences of this trend, it behooves dermatologists to maximize use of non-antimicrobial therapy when treating acne. In this review of the literature we present data regarding the efficacy and appropriate use of non-antimicrobial treatments for acne. A variety of topical and oral treatment options exist that can be used in a step-wise manner according to the patients’ severity and therapeutic response. Non-antimicrobial treatments can be highly efficacious at controlling acne, especially when used as maintenance therapy. While antibiotics have a role in acne treatment, they should not be used as monotherapy, and lengthy courses of antibiotic use are discouraged.
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