The study of in vivo quantification of aluminum (Al) in human bone with a compact DD generator-based neutron activation analysis (NAA) system.

The study of in vivo quantification of aluminum (Al) in human bone with a compact DD generator-based neutron activation analysis (NAA) system.
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DOI:
10.1088/0967-3334/37/5/649
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发表时间:
2016-05
影响因子:
3.2
通讯作者:
Nie LH
Nie LH
中科院分区:
工程技术3区
文献类型:
--
作者:
Byrne P;Mostafaei F;Liu Y;Blake SP;Koltick D;Nie LH

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本文研究了用小型DD发生器中子活化分析系统测定手骨中铝的可行性和方法。蒙特卡罗模拟被用来模拟慢化剂,反射器和屏蔽组件,并估计辐射剂量。采用高纯锗探测器探测Al γ射线信号。最低检测限(MDL)为11.13 μg g−1干骨(ppm)。额外的HPGe探测器将使MDL提高1.4倍,达到7.9 ppm。通过Monte Carlo计算,传递到受照射手部的等效剂量为11.9 mSv。发现使用DD发生器进行体内骨铝测量在一般人群中是可行的,受试者可接受剂量。
The feasibility and methodology of using a compact DD generator-based neutron activation analysis system to measure aluminum in hand bone has been investigated. Monte Carlo simulations were used to simulate the moderator, reflector, and shielding assembly and to estimate the radiation dose. A high purity germanium (HPGe) detector was used to detect the Al gamma ray signals. The minimum detectable limit (MDL) was found to be 11.13 μg g−1 dry bone (ppm). An additional HPGe detector would improve the MDL by a factor of 1.4, to 7.9 ppm. The equivalent dose delivered to the irradiated hand was calculated by Monte Carlo to be 11.9 mSv. In vivo bone aluminum measurement with the DD generator was found to be feasible among general population with an acceptable dose to the subject.
DOI: 10.1007/bf02516952
发表时间: 1980-01-01
期刊: JOURNAL OF RADIOANALYTICAL CHEMISTRY
影响因子: --
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