Engineering peripheral nerve repair.
Engineering peripheral nerve repair.
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DOI:
10.1016/j.copbio.2013.05.006
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发表时间:
2013-10
影响因子:
7.7
通讯作者:
Sakiyama-Elbert, Shelly E.
中科院分区:
文献类型:
--
作者:
Marquardt, Laura M.;Sakiyama-Elbert, Shelly E.
Current approaches for treating peripheral nerve injury have resulted in promising, yet insufficient functional recovery compared to the clinical standard of care, autologous nerve grafts. In order to design a construct that can match the regenerative potential of the autograft, all facets of nerve tissue must be incorporated in a combinatorial therapy. Engineered biomaterial scaffolds in the future will have to promote enhanced regeneration and appropriate reinnervation by targeting the highly sensitive response of regenerating nerves to their surrounding microenvironment.
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