Monitoring occurrence of SARS-CoV-2 in school populations: A wastewater-based approach.

Monitoring occurrence of SARS-CoV-2 in school populations: A wastewater-based approach.
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DOI:
10.1371/journal.pone.0270168
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发表时间:
2022
期刊:
影响因子:
3.7
通讯作者:
Di Cesare M
Di Cesare M
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Castro-Gutierrez V;Hassard F;Vu M;Leitao R;Burczynska B;Wildeboer D;Stanton I;Rahimzadeh S;Baio G;Garelick H;Hofman J;Kasprzyk-Hordern B;Kwiatkowska R;Majeed A;Priest S;Grimsley J;Lundy L;Singer AC;Di Cesare M

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Clinical testing of children in schools is challenging, with economic implications limiting its frequent use as a monitoring tool of the risks assumed by children and staff during the COVID-19 pandemic. Here, a wastewater-based epidemiology approach has been used to monitor 16 schools (10 primary, 5 secondary and 1 post-16 and further education) in England. A total of 296 samples over 9 weeks have been analysed for N1 and E genes using qPCR methods. Of the samples returned, 47.3% were positive for one or both genes with a detection frequency in line with the respective local community. WBE offers a low cost, non-invasive approach for supplementing clinical testing and can provide longitudinal insights that are impractical with traditional clinical testing.
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