Implementing building-level SARS-CoV-2 wastewater surveillance on a university campus.
Implementing building-level SARS-CoV-2 wastewater surveillance on a university campus.
复制标题
DOI：
10.1016/j.scitotenv.2021.146749
复制
发表时间：
2021-08-15
期刊：
影响因子：
--
通讯作者：
Munir M
中科院分区：
文献类型：
--
作者：
Gibas C;Lambirth K;Mittal N;Juel MAI;Barua VB;Roppolo Brazell L;Hinton K;Lontai J;Stark N;Young I;Quach C;Russ M;Kauer J;Nicolosi B;Chen D;Akella S;Tang W;Schlueter J;Munir M
COVID-19大流行一直是持续挑战的来源，并增加了群体环境中的疾病风险，包括监狱、长期护理设施、学校和住宿大学校园。早期报告称，在确诊病例之前，可以在废水中检测到SARS-CoV-2病毒，这引发了人们对基于废水的流行病学（WBE）作为缓解COVID-19爆发的工具的广泛兴趣。一种假设是，废水监测可能提供一种成本效益高的替代办法，取代其他更昂贵的办法，如对群体进行集中和随机测试。在本文中，我们报告的结果，废水监测试点计划在北卡罗来纳州大学在夏洛特，一个大型的城市大学，大量的学生住在校园宿舍。在整个大学秋季住宿学期，每周三次在建筑物一级进行监测。在多个案例中，废水监测使校园监测计划的其他组成部分未能发现的无症状COVID-19病例得以识别，该计划还包括内部接触者追踪、症状检测、学生运动员的定期检测和每日症状报告。在秋季学期向大学社区报告的所有集群事件的背景下，基于废水的测试事件导致识别出比其他类型的集群事件中报告的集群更小的集群。废水监测能够在居住人口为150-200人的宿舍中检测到单个无症状个体。虽然所述策略是为COVID-19而制定的，但它可能适用于缓解大学和其他群体生活环境中的未来流行病。
The COVID-19 pandemic has been a source of ongoing challenges and presents an increased risk of illness in group environments, including jails, long-term care facilities, schools, and residential college campuses. Early reports that the SARS-CoV-2 virus was detectable in wastewater in advance of confirmed cases sparked widespread interest in wastewater-based epidemiology (WBE) as a tool for mitigation of COVID-19 outbreaks. One hypothesis was that wastewater surveillance might provide a cost-effective alternative to other more expensive approaches such as pooled and random testing of groups. In this paper, we report the outcomes of a wastewater surveillance pilot program at the University of North Carolina at Charlotte, a large urban university with a substantial population of students living in on-campus dormitories. Surveillance was conducted at the building level on a thrice-weekly schedule throughout the university's fall residential semester. In multiple cases, wastewater surveillance enabled the identification of asymptomatic COVID-19 cases that were not detected by other components of the campus monitoring program, which also included in-house contact tracing, symptomatic testing, scheduled testing of student athletes, and daily symptom reporting. In the context of all cluster events reported to the University community during the fall semester, wastewater-based testing events resulted in the identification of smaller clusters than were reported in other types of cluster events. Wastewater surveillance was able to detect single asymptomatic individuals in dorms with resident populations of 150–200. While the strategy described was developed for COVID-19, it is likely to be applicable to mitigation of future pandemics in universities and other group-living environments.
登录
查看更多内容
影响因子：
7.7
作者：
Lago, PM;Gary, HE;Cruz, RG
通讯作者：
Cruz, RG
影响因子：
2.5
作者：
Haramoto, E.;Kitajima, M.;Ohgaki, S.
通讯作者：
Ohgaki, S.
影响因子：
12.8
作者：
McCall, Camille;Wu, Huiyun;Xagoraraki, Irene
通讯作者：
Xagoraraki, Irene
影响因子：
5.2
作者：
Travis SA;Best AA;Bochniak KS;Dunteman ND;Fellinger J;Folkert PD;Koberna T;Kopek BG;Krueger BP;Pestun J;Pikaart MJ;Sabo C;Schuitema AJ
通讯作者：
Schuitema AJ
DOI：
10.1016/j.scitotenv.2021.146408
发表时间：
2021-07-20
期刊：
The Science of the total environment
影响因子：
--
作者：
Betancourt WQ;Schmitz BW;Innes GK;Prasek SM;Pogreba Brown KM;Stark ER;Foster AR;Sprissler RS;Harris DT;Sherchan SP;Gerba CP;Pepper IL
通讯作者：
Pepper IL