Differential expression of the Tmem132 family genes in the developing mouse nervous system.
Differential expression of the Tmem132 family genes in the developing mouse nervous system.
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DOI：
10.1016/j.gep.2022.119257
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发表时间：
2022-09
影响因子：
1.2
通讯作者：
Liu, Aimin
中科院分区：
文献类型：
--
作者：
Wang, Yuan;Herzig, Graham;Molano, Cassandra;Liu, Aimin
关键词：
新型跨膜蛋白（TMEM） 132家族与人类多种神经系统疾病和癌症有关，但很少在体内进行研究。在这里，我们用RNA原位杂交技术报道了发育中的小鼠神经系统中5个Tmem132基因（a、b、c、d和e）的表达模式。我们的研究结果揭示了多个Tmem132家族成员在中枢和外周神经系统中的差异和部分重叠表达，表明它们之间可能存在部分冗余。
The family of novel transmembrane proteins (TMEM) 132 have been associated with multiple neurological disorders and cancers in humans, but have hardly been studied in vivo. Here we report the expression patterns of the five Tmem132 genes (a, b, c, d and e) in developing mouse nervous system with RNA in situ hybridization in wholemount embryos and tissue sections. Our results reveal differential and partially overlapping expression of multiple Tmem132 family members in both the central and peripheral nervous system, suggesting potential partial redundancy among them.
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影响因子：
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Karapetsas A;Giannakakis A;Dangaj D;Lanitis E;Kynigopoulos S;Lambropoulou M;Tanyi JL;Galanis A;Kakolyris S;Trypsianis G;Coukos G;Sandaltzopoulos R
通讯作者：
Sandaltzopoulos R
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Niswander LA
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JOYNER, AL
影响因子：
64.8
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通讯作者：
Murray SA