Social determinants of antenatal depression and anxiety among women in South Asia: A systematic review & meta-analysis.

Social determinants of antenatal depression and anxiety among women in South Asia: A systematic review & meta-analysis.
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DOI:
10.1371/journal.pone.0263760
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发表时间:
2022
期刊:
影响因子:
3.7
通讯作者:
Rankin J
Rankin J
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Insan N;Weke A;Forrest S;Rankin J

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怀孕是一个主要的心理变化的时期,使孕妇更容易抑郁和焦虑。与高收入国家相比,生活在孟加拉国、印度和巴基斯坦的妇女的患病率较高,这是由于对产前保健了解不足和缺乏将精神卫生纳入产前保健。产前抑郁/焦虑与不良后果相关,包括产后抑郁、低出生体重和胎儿发育受损。现有的系统评价仅提供了这些南亚国家产前抑郁/焦虑的社会决定因素的有限信息。本综述旨在识别、综合和评估与孟加拉国、印度和巴基斯坦妇女产前抑郁和焦虑相关的社会决定因素的证据。我们检索了5个数据库(MEDLINE, Embase, PsycINFO, Scopus, Web of Science)和PROSPERO。2000年1月1日至2021年1月4日期间发表的观察性研究,如果是用英语发表的,使用了有效的工具来测量孕妇的抑郁/焦虑,并报告了统计关联或原始数据,则纳入研究。采用随机效应模型进行汇总估计。异质性和发表偏倚分别采用I2统计量和Egger检验。本综述已在PROSPERO注册(参考编号:CRD42020167903)。我们纳入了34项研究(27379名女性)。调整优势比(AOR)的meta分析发现,亲密伴侣暴力(AOR 2.48, 95% CI 1.41-4.33)、意外怀孕(AOR 1.53, 95% CI 1.28-1.83)、男性性别偏好(AOR 3.06, 95% CI 1.40-6.72)和与姻亲关系不佳(AOR 2.69, 95% CI 1.25-5.80)与产前抑郁/焦虑显著相关。该审查确定了孟加拉国、印度和巴基斯坦产前抑郁和焦虑的一系列复杂的社会决定因素。应将识别高危孕妇的筛查工具纳入产前保健,以预防不良后果。了解这些社会决定因素将有助于开发此类筛查工具和干预措施。
Pregnancy is a time of major psychological changes making pregnant women more susceptible to depression and anxiety. Prevalence is higher among women living in Bangladesh, India and Pakistan, compared to high-income countries, due to poor understanding and lack of mental health integration within antenatal care. Antenatal depression/anxiety is associated with adverse outcomes including postnatal depression, low birth weight and impaired fetal development. Existing systematic reviews provided only limited information on the social determinants of antenatal depression/anxiety in these South Asian countries. This review aimed to identify, synthesise and appraise the evidence on the social determinants associated with antenatal depression and anxiety in women living in Bangladesh, India and Pakistan. We searched five databases (MEDLINE, Embase, PsycINFO, Scopus, Web of Science) and PROSPERO. Observational studies published between 1st January 2000 and 4th January 2021 were included if they were in the English language, used validated tools for measuring depression/anxiety in pregnant women and reported statistical associations or raw numbers. Summary estimates were obtained using random-effects model. Heterogeneity and publication bias was measured using the I2 statistic and Egger’s test, respectively. This review was registered on PROSPERO (reference: CRD42020167903). We included 34 studies (with 27,379 women). Meta-analysis of Adjusted Odds Ratios (AOR) found that Intimate partner violence (AOR 2.48, 95% CI 1.41–4.33), unplanned pregnancy (AOR 1.53, 95% CI 1.28–1.83), male gender preference (AOR 3.06, 95% CI 1.40–6.72) and poor relationship with in-laws (AOR 2.69, 95% CI 1.25–5.80) were significantly associated with antenatal depression/anxiety. The review identified a complex range of social determinants of antenatal depression and anxiety in Bangladesh, India and Pakistan. Screening tools to identify pregnant women at high risk should be integrated within antenatal care to prevent adverse outcomes. Knowledge of these social determinants will inform the development of such screening tools and interventions.
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