Oral health conditions and COVID-19: A systematic review and meta-analysis of the current evidence.
Oral health conditions and COVID-19: A systematic review and meta-analysis of the current evidence.
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DOI：
10.1016/j.ahr.2022.100064
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发表时间：
2022-03
影响因子：
--
通讯作者：
Wu B
中科院分区：
文献类型：
--
作者：
Qi X;Northridge ME;Hu M;Wu B
2019冠状病毒病（COVID-19）大流行凸显了了解导致COVID-19的潜在条件的重要性。口腔健康在维持健康状态方面具有系统性影响。本研究旨在总结COVID-19参与者口腔健康状况患病率的证据，并评估口腔健康状况与COVID-19相关结果之间的关联。检索了2019年12月1日至2021年3月1日期间的5个数据库和灰色文献。报告了COVID-19参与者的口腔健康状况和/或检查了口腔健康与COVID-19之间的关联的研究也包括在内。我们发现了15篇文章，涵盖了来自10个国家的5，377名COVID-19参与者。口干是最常见的口腔健康状况（41.0%），其次是口腔病变（38.8%），口面部疼痛（18.3%）和牙周症状（11.7%）。根据汇总比值比（OR），牙周症状与COVID-19阳性（OR = 1.1; 95%置信区间[CI]，0.73-1.65）或死亡率（OR = 2.71; 95% CI，0.64-11.51）无关，但与COVID-19严重程度相关（OR = 3.18; 95% CI，1.81-5.58）。口腔健康状况在COVID-19参与者中很常见，应在这种疾病的发作和进展中加以考虑。这方面的知识仍然有限，所提取的数据质量很低。需要进一步的纵向研究来确定口腔健康状况是否是SARS-CoV-2感染的结果，或者它们是否早于感染并是COVID-19的风险因素。
The coronavirus disease 2019 (COVID-19) pandemic has highlighted the importance of understanding the underlying conditions that lead to COVID-19. Oral health has systemic implications in the maintenance of a healthy state. This study aimed to summarize evidence on the prevalence of oral health conditions in participants with COVID-19 and assess the associations between oral health conditions and COVID-19 related outcomes. Article searches were conducted in five databases and the gray literature from December 1, 2019 to March 1, 2021. Studies that reported oral health conditions for participants with COVID-19 and/or examined associations between oral health and COVID-19 were included. We identified 15 articles that encompassed 5,377 participants with COVID-19 from 10 countries. Dry mouth was the most common oral health condition reported (41.0%), followed by oral lesions (38.8%), orofacial pain (18.3%), and periodontal symptoms (11.7%). Based on the pooled odds ratios (ORs), periodontal symptoms were not associated with COVID-19 positivity (OR = 1.1; 95% confidence intervals [CI], 0.73–1.65) or mortality (OR = 2.71; 95% CI, 0.64–11.51), but were associated with COVID-19 severity (OR = 3.18; 95% CI, 1.81–5.58). Oral health conditions are common in participants with COVID-19 and should be considered in both the onset and progression of this disease. Knowledge in this area is still limited, and the quality of the data extracted was low. Further longitudinal studies are needed to ascertain whether oral health conditions are a consequence of infection with SARS-CoV-2 or whether they predate infection and are risk factors for COVID-19.
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DOI：
10.1136/bmj.b2535
发表时间：
2009-07-21
期刊：
BMJ (Clinical research ed.)
影响因子：
--
作者：
Moher D;Liberati A;Tetzlaff J;Altman DG;PRISMA Group
通讯作者：
PRISMA Group
影响因子：
6.7
作者：
Marouf N;Cai W;Said KN;Daas H;Diab H;Chinta VR;Hssain AA;Nicolau B;Sanz M;Tamimi F
通讯作者：
Tamimi F
影响因子：
3.9
作者：
Larvin H;Wilmott S;Wu J;Kang J
通讯作者：
Kang J
影响因子：
0.7
作者：
Manzalawi R;Alhmamey K;Abdelrasoul M
通讯作者：
Abdelrasoul M
影响因子：
3.9
作者：
Hocková B;Riad A;Valky J;Šulajová Z;Stebel A;Slávik R;Bečková Z;Pokorná A;Klugarová J;Klugar M
通讯作者：
Klugar M