Hippocampal Resting State Functional Connectivity Associated with Physical Activity in Periadolescent Children.
Hippocampal Resting State Functional Connectivity Associated with Physical Activity in Periadolescent Children.
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DOI：
10.3390/brainsci13111558
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发表时间：
2023-11-07
期刊：
影响因子：
3.3
通讯作者：
中科院分区：
文献类型：
--
作者：
围青春期是一个神经发育时期，其特征是与认知成熟相关的结构和功能性大脑变化。海马功能连接的发展有助于认知成熟，特别是记忆过程。值得注意的是，海马体的发育受到生活方式因素的影响，包括身体活动。体力活动与海马功能连接的个体差异有关。然而，这种关系尚未在发育队列中得到表征。在这项研究中，我们的目的是填补这一空白，通过调查之间的关系，身体活动和海马功能连接在一个队列的年龄8-13岁的青少年（N = 117）。参与者完成了一份体力活动问卷，报告了他们每周进行60分钟体力活动的天数;然后，他们完成了静息状态功能性MRI扫描。我们观察到，更多的体力活动与额叶和颞叶海马功能连接的差异显着相关。更多的体力活动与海马体和右侧上级额回之间的连接性降低以及海马体和左侧上级颞沟之间的连接性增加有关。在关键发育时期捕捉海马功能连接的变化可能会阐明包括身体活动在内的生活方式因素如何影响大脑网络连接轨迹，认知发展和未来疾病风险。
Periadolescence is a neurodevelopmental period characterized by structural and functional brain changes that are associated with cognitive maturation. The development of the functional connectivity of the hippocampus contributes to cognitive maturation, especially memory processes. Notably, hippocampal development is influenced by lifestyle factors, including physical activity. Physical activity has been associated with individual variability in hippocampal functional connectivity. However, this relationship has not been characterized in a developmental cohort. In this study, we aimed to fill this gap by investigating the relationship between physical activity and the functional connectivity of the hippocampus in a cohort of periadolescents aged 8–13 years (N = 117). The participants completed a physical activity questionnaire, reporting the number of days per week they performed 60 min of physical activity; then, they completed a resting-state functional MRI scan. We observed that greater physical activity was significantly associated with differences in hippocampal functional connectivity in frontal and temporal regions. Greater physical activity was associated with decreased connectivity between the hippocampus and the right superior frontal gyrus and increased connectivity between the hippocampus and the left superior temporal sulcus. Capturing changes in hippocampal functional connectivity during key developmental periods may elucidate how lifestyle factors including physical activity influence brain network connectivity trajectories, cognitive development, and future disease risk.
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影响因子：
3.3
作者：
Voss, M. W.;Chaddock, L.;Kim, J. S.;Vanpatter, M.;Pontifex, M. B.;Raine, L. B.;Cohen, N. J.;Hillman, C. H.;Kramer, A. F.
通讯作者：
Kramer, A. F.
影响因子：
2.9
作者：
Chaddock L;Erickson KI;Prakash RS;Kim JS;Voss MW;Vanpatter M;Pontifex MB;Raine LB;Konkel A;Hillman CH;Cohen NJ;Kramer AF
通讯作者：
Kramer AF
影响因子：
3.2
作者：
Corbetta, M;Kincade, JM;Shulman, GL
通讯作者：
Shulman, GL
影响因子：
3.4
作者：
Ikuta, Toshikazu;Loprinzi, Paul D.
通讯作者：
Loprinzi, Paul D.
影响因子：
4.7
作者：
Casey BJ;Cannonier T;Conley MI;Cohen AO;Barch DM;Heitzeg MM;Soules ME;Teslovich T;Dellarco DV;Garavan H;Orr CA;Wager TD;Banich MT;Speer NK;Sutherland MT;Riedel MC;Dick AS;Bjork JM;Thomas KM;Chaarani B;Mejia MH;Hagler DJ Jr;Daniela Cornejo M;Sicat CS;Harms MP;Dosenbach NUF;Rosenberg M;Earl E;Bartsch H;Watts R;Polimeni JR;Kuperman JM;Fair DA;Dale AM;ABCD Imaging Acquisition Workgroup
通讯作者：
ABCD Imaging Acquisition Workgroup