Inspiratory Muscle Training for Obstructive Sleep Apnea: Protocol Development and Feasibility of Home Practice by Sedentary Adults.
Inspiratory Muscle Training for Obstructive Sleep Apnea: Protocol Development and Feasibility of Home Practice by Sedentary Adults.
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DOI：
10.3389/fphys.2021.737493
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发表时间：
2021
影响因子：
4
通讯作者：
Macey PM
中科院分区：
文献类型：
--
作者：
Krause-Sorio B;An E;Aguila AP;Martinez F;Aysola RS;Macey PM
背景资料：吸气肌训练（IMT）可以改善阻塞性睡眠呼吸暂停（OSA）患者的呼吸和心血管功能，是持续气道正压通气（CPAP）的潜在替代或辅助治疗。IMT方案最初是为运动员设计的，然而，我们发现一些OSA患者无法进行运动，因此我们的目标是制定一个更适合OSA的方案。我们的可行性标准包括：（1）参与者在家中成功管理该技术;（2）参与者完成日常练习并记录数据日志;（3）捕获性能平台以确定干预的最佳长度。方法：5名久坐型OSA患者参加了这项可行性研究（3名男性，平均年龄= 61.6岁，SD = 10.2）。使用数字POWERbreathe K4或K5设备，参与者每天进行30次吸入，阻力设定为最大值的百分比，每周重新计算。参与者愿意每天进行一次而不是两次练习。根据能力和主观反馈调整常见IMT方案的干预参数。有些人无法完成通常使用的最大吸气阻力的75%，因此我们将目标降低到65%。这项技术需要一些练习;因此，我们引入了一个练习周，目标是50%。在最初的8周后，干预是开放式的，训练持续到所有参与者表现出至少一个吸气强度的平台（2周没有力量增加）。每周电子邮件和电话提醒确保参与者完成所有日常课程并在在线调查中记录数据。每周测量吸气阻力、强度、容量和流量。结果：参与者成功地完成了实践和随后的65% IMT阻力目标，每天持续13周。在10周的训练结束时，所有受试者的吸气强度增益都显示出平台，这表明12周加练习足以实现并捕获最大增益。参与者报告没有不良反应。结论：我们在一小组久坐不动、未经治疗的OSA患者中开发并测试了13周IMT方案。相对于其他IMT协议，我们成功地实现了降低的性能要求，一个练习周，并延长了时间框架。这项可行性研究为OSA中IMT的临床试验方案提供了基础。
Background: Inspiratory muscle training (IMT) may improve respiratory and cardiovascular functions in obstructive sleep apnea (OSA) and is a potential alternative or adjunct treatment to continuous positive airway pressure (CPAP). IMT protocols were originally designed for athletes, however, we found some OSA patients could not perform the exercise, so we aimed for a more OSA-friendly protocol. Our feasibility criteria included (1) participants successfully managing the technique at home; (2) participants completing daily practice sessions and recording data logs; and (3) capturing performance plateaus to determine an optimal length of the intervention. Methods: Five sedentary OSA patients participated in this feasibility study (three men, mean age = 61.6 years, SD = 10.2). Using a digital POWERbreathe K4 or K5 device, participants performed 30 daily inhalations against a resistance set at a percentage of maximum, recalculated weekly. Participants were willing to perform one but not two daily practice sessions. Intervention parameters from common IMT protocols were adapted according to ability and subjective feedback. Some were unable to perform the typically used 75% of maximum inspiratory resistance so we lowered the target to 65%. The technique required some practice; therefore, we introduced a practice week with a 50% target. After an initial 8 weeks, the intervention was open-ended and training continued until all participants demonstrated at least one plateau of inspiratory strength (2 weeks without strength gain). Weekly email and phone reminders ensured that participants completed all daily sessions and logged data in their online surveys. Weekly measures of inspiratory resistance, strength, volume, and flow were recorded. Results: Participants successfully completed the practice and subsequent 65% IMT resistance targets daily for 13 weeks. Inspiratory strength gains showed plateaus in all subjects by the end of 10 weeks of training, suggesting 12 weeks plus practice would be sufficient to achieve and capture maximum gains. Participants reported no adverse effects. Conclusion: We developed and tested a 13-week IMT protocol in a small group of sedentary, untreated OSA patients. Relative to other IMT protocols, we successfully implemented reduced performance requirements, a practice week, and an extended timeframe. This feasibility study provides the basis for a protocol for clinical trials on IMT in OSA.
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影响因子：
24
作者：
Javaheri S;Barbe F;Campos-Rodriguez F;Dempsey JA;Khayat R;Javaheri S;Malhotra A;Martinez-Garcia MA;Mehra R;Pack AI;Polotsky VY;Redline S;Somers VK
通讯作者：
Somers VK
DOI：
10.1519/jsc.0b013e318269f73f
发表时间：
2013-06-01
影响因子：
3.2
作者：
HajGhanbari, Bahareh;Yamabayashi, Cristiane;Reid, W. Darlene
通讯作者：
Reid, W. Darlene
影响因子：
4.3
作者：
Marshall, Nathaniel S.;Wong, Keith K. H.;Grunstein, Ronald R.
通讯作者：
Grunstein, Ronald R.
影响因子：
2.5
作者：
Posser, Simone Regina;Callegaro, Carine Cristina;Moreira, Leila Beltrami
通讯作者：
Moreira, Leila Beltrami
影响因子：
24
作者：
Monahan, Ken;Storfer-Isser, Amy;Mehra, Reena;Shahar, Eyal;Mittleman, Murray;Rottman, Jeff;Punjabi, Naresh;Sanders, Mark;Quan, Stuart F.;Resnick, Helaine;Redline, Susan
通讯作者：
Redline, Susan