DSM-5 and RDoC: progress in psychiatry research?

DSM-5 and RDoC: progress in psychiatry research?
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DOI:
10.1038/nrn3621
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发表时间:
2013-11
影响因子:
34.7
通讯作者:
Ressler, Kerry J.
Ressler, Kerry J.
中科院分区:
医学1区
文献类型:
--
作者:
Casey, B. J.;Craddock, Nick;Cuthbert, Bruce N.;Hyman, Steven E.;Lee, Francis S.;Ressler, Kerry J.

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神经科学对精神疾病的研究通常依赖于基于有影响力的精神疾病诊断和统计手册(DSM)的疾病定义,该手册的第五版(DSM-5)于今年早些时候发布。DSM被设计为一个纯粹的诊断工具,将不同的疾病视为不同的实体。然而,疾病之间的界限往往不像DSM所建议的那样严格。为了给精神疾病的研究提供一个可供选择的框架,美国国家精神卫生研究所(NIMH)最近推出了其研究领域标准(RDoC)项目。在RDoC中,五个“域”每个都反映了一个大脑系统,其中功能在不同的精神状况下受到不同程度的损害。《自然评论神经科学》就DSM-5和RDoC将如何影响神经科学对精神疾病的研究询问了六位主要研究人员的想法。
Neuroscience studies into psychiatric disorders generally rely on disease definitions that are based on the influential Diagnostic and Statistical Manual of Mental Disorders (DSM), the fifth edition of which (DSM-5) was released earlier this year. Designed as a purely diagnostic tool, the DSM considers different disorders as distinct entities. However, boundaries between disorders are often not as strict as the DSM suggests. To provide an alternative framework for research into psychiatric disorders, the US National Institute of Mental Health (NIMH) has recently introduced its Research Domain Criteria (RDoC) project. In the RDoC, five ‘domains’ each reflect a brain system in which functioning is impaired, to different degrees, in different psychiatric conditions. Nature Reviews Neuroscience asked six leading investigators for their thoughts on how DSM-5 and the RDoC will influence neuroscience research into psychiatric disorders.
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发表时间: 2013-06-01
影响因子: 10.6
作者:
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