Microbial Sharing between Pediatric Patients and Therapy Dogs during Hospital Animal-Assisted Intervention Programs.
Microbial Sharing between Pediatric Patients and Therapy Dogs during Hospital Animal-Assisted Intervention Programs.
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DOI：
10.3390/microorganisms9051054
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发表时间：
2021-05-13
期刊：
影响因子：
4.5
通讯作者：
Davis MF
中科院分区：
文献类型：
--
作者：
Dalton KR;Ruble K;Redding LE;Morris DO;Mueller NT;Thorpe RJ Jr;Agnew J;Carroll KC;Planet PJ;Rubenstein RC;Chen AR;Grice EA;Davis MF
人类和动物之间的微生物共享已在各种环境中得到证实。然而，在动物辅助干预计划期间，医疗机构内发生的微生物共享程度尚不清楚。了解患者和治疗犬之间的微生物传播可以为患者提供潜在健康益处的重要见解，此外还可以解决限制计划利用的潜在病原体传播问题。本研究评价了儿科患者和治疗犬之间的潜在微生物共享，并测试了患者-犬接触水平和犬去殖民化方案是否改变了这种共享。在每组治疗前后对患者、治疗犬和医院环境进行采样，并对样本进行16 S rRNA测序以表征微生物群落。患者和狗的鼻腔微生物组的相对丰度和总体多样性都发生了变化，这表明微生物的交换已经发生。接触的增加与患者和治疗犬之间以及患者之间的更多分享有关。局部洗必泰为基础的狗去殖民化与治疗狗和患者之间的微生物共享减少，但没有显着影响患者之间的共享。这些数据表明，治疗犬既是向患者转移微生物的潜在来源，也是向患者转移微生物的载体，但不一定是唯一来源。其他潜在来源的相对贡献（例如，其他病人，医院环境）应进一步探讨，以确定其相对重要性。
Microbial sharing between humans and animals has been demonstrated in a variety of settings. However, the extent of microbial sharing that occurs within the healthcare setting during animal-assisted intervention programs is unknown. Understanding microbial transmission between patients and therapy dogs can provide important insights into potential health benefits for patients, in addition to addressing concerns regarding potential pathogen transmission that limits program utilization. This study evaluated for potential microbial sharing between pediatric patients and therapy dogs and tested whether patient–dog contact level and a dog decolonization protocol modified this sharing. Patients, therapy dogs, and the hospital environment were sampled before and after every group therapy session and samples underwent 16S rRNA sequencing to characterize microbial communities. Both patients and dogs experienced changes in the relative abundance and overall diversity of their nasal microbiome, suggesting that the exchange of microorganisms had occurred. Increased contact was associated with greater sharing between patients and therapy dogs, as well as between patients. A topical chlorhexidine-based dog decolonization was associated with decreased microbial sharing between therapy dogs and patients but did not significantly affect sharing between patients. These data suggest that the therapy dog is both a potential source of and a vehicle for the transfer of microorganisms to patients but not necessarily the only source. The relative contribution of other potential sources (e.g., other patients, the hospital environment) should be further explored to determine their relative importance.
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DOI：
10.1186/1710-1492-9-15
发表时间：
2013
期刊：
Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology
影响因子：
--
作者：
Azad MB;Konya T;Maughan H;Guttman DS;Field CJ;Sears MR;Becker AB;Scott JA;Kozyrskyj AL
通讯作者：
Kozyrskyj AL
影响因子：
48
作者：
Callahan BJ;McMurdie PJ;Rosen MJ;Han AW;Johnson AJ;Holmes SP
通讯作者：
Holmes SP
影响因子：
3
作者：
Dalton KR;Waite KB;Ruble K;Carroll KC;DeLone A;Frankenfield P;Serpell JA;Thorpe RJ Jr;Morris DO;Agnew J;Rubenstein RC;Davis MF
通讯作者：
Davis MF
影响因子：
15.5
作者：
Fadrosh DW;Ma B;Gajer P;Sengamalay N;Ott S;Brotman RM;Ravel J
通讯作者：
Ravel J
影响因子：
26.1
作者：
Fall, Tove;Lundholm, Cecilia;Almqvist, Catarina
通讯作者：
Almqvist, Catarina