Effects of oils rich in linoleic and α-linolenic acids on fatty acid profile and gene expression in goat meat.

Effects of oils rich in linoleic and α-linolenic acids on fatty acid profile and gene expression in goat meat.
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DOI:
10.3390/nu6093913
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发表时间:
2014-09-24
期刊:
影响因子:
5.9
通讯作者:
Goh YM
Goh YM
中科院分区:
医学2区
文献类型:
--
作者:
Ebrahimi M;Rajion MA;Goh YM

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改变食品的脂质含量和脂肪酸 (FA) 成分可以生产出更健康的产品。本研究的目的是确定山羊饮食中亚麻籽油或葵花籽油对肌肉脂肪酸组成和半腱肌 (ST) 肌肉中脂肪生成基因表达的影响。 21只雄性波尔小山羊饲喂含有不同水平的亚油酸(LA)和α-亚麻酸(LNA)的饲料100天。亚麻籽油的加入增加了 ST 肌中 α-亚麻酸 (C18:3n-3) 的浓度 (p < 0.05)。富含 α-亚麻酸 (p < 0.05) 的饮食降低了 ST 肌中花生四烯酸 (C20:4n-6) 和共轭亚麻酸 (CLA) c-9 t-11 的含量。与低α-亚麻酸组相比,高α-亚麻酸组ST肌中PPARα和PPARγ基因表达显着上调(p < 0.05),硬脂酰辅酶A去饱和酶(SCD)基因下调。本研究结果表明,亚麻籽油作为α-亚麻酸的来源,可以添加到山羊日粮中,以丰富山羊肉中的n-3脂肪酸,上调PPARα和PPARγ,并下调SCD基因表达。
Alteration of the lipid content and fatty acid (FA) composition of foods can result in a healthier product. The aim of this study was to determine the effect of flaxseed oil or sunflower oil in the goat diet on fatty acid composition of muscle and expression of lipogenic genes in the semitendinosus (ST) muscle. Twenty-one entire male Boer kid goats were fed diets containing different levels of linoleic acid (LA) and α-linolenic acid (LNA) for 100 days. Inclusion of flaxseed oil increased (p < 0.05) the α-linolenic acid (C18:3n-3) concentration in the ST muscle. The diet high in α-linolenic acid (p < 0.05) decreased the arachidonic acid (C20:4n-6) and conjugated linolenic acid (CLA) c-9 t-11 content in the ST muscle. There was a significant (p < 0.05) upregulation of PPARα and PPARγ gene expression and downregulation of stearoyl-CoA desaturase (SCD) gene in the ST muscle for the high α-linolenic acid group compared with the low α-linolenic acid group. The results of the present study show that flaxseed oil as a source of α-linolenic acid can be incorporated into the diets of goats to enrich goat meat with n-3 fatty acids, upregulate the PPARα and PPARγ, and downregulate the SCD gene expression.
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