Effect of linseed oil dietary supplementation on fatty acid composition and gene expression in adipose tissue of growing goats.
Effect of linseed oil dietary supplementation on fatty acid composition and gene expression in adipose tissue of growing goats.
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DOI：
10.1155/2013/194625
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发表时间：
2013
影响因子：
--
通讯作者：
Schonewille JT
中科院分区：
文献类型：
--
作者：
Ebrahimi M;Rajion MA;Goh YM;Sazili AQ;Schonewille JT
本试验旨在研究添加高α-亚麻酸（C18：3 n-3）亚麻籽油（LO）的油棕榈叶青贮日粮（HLO、LLO）和不添加LO的对照组（CON）对波尔山羊皮下脂肪组织脂肪酸组成及过氧化物酶体增殖物激活受体（PPAR）α、PPAR-γ和硬脂酰辅酶A去饱和酶（SCD）基因表达的影响。皮下脂肪中C18：3 n-3的比例随日粮中LO水平的增加而增加（P < 0.01），表明HLO产生的FA可能逃避了瘤胃的生物氢化。与喂食CON饲料的动物相比，喂食HLO饲料的动物皮下脂肪组织中C18：1 trans-11、C18：2n-6、CLA cis-9 trans-11和C20：4 n-6的比例较低，C18：3 n-3、C22：5 n-3和C22：6 n-3的比例较高，导致组织中n-6：n-3脂肪酸比（FAR）降低。此外，HLO组大鼠脂肪组织中PPAR-γ的表达显著上调（P < 0.05），SCD的表达显著下调（P < 0.05）。本研究的结果表明，LO可以安全地掺入山羊的饮食中，以丰富山羊肉中潜在的健康有益FA（即，n-3FA）。
This study was conducted to determine the effects of feeding oil palm frond silage based diets with added linseed oil (LO) containing high α-linolenic acid (C18:3n-3), namely, high LO (HLO), low LO (LLO), and without LO as the control group (CON) on the fatty acid (FA) composition of subcutaneous adipose tissue and the gene expression of peroxisome proliferator-activated receptor (PPAR)α, PPAR-γ, and stearoyl-CoA desaturase (SCD) in Boer goats. The proportion of C18:3n-3 in subcutaneous adipose tissue was increased (P < 0.01) by increasing the LO in the diet, suggesting that the FA from HLO might have escaped ruminal biohydrogenation. Animals fed HLO diets had lower proportions of C18:1 trans-11, C18:2n-6, CLA cis-9 trans-11, and C20:4n-6 and higher proportions of C18:3n-3, C22:5n-3, and C22:6n-3 in the subcutaneous adipose tissue than animals fed the CON diets, resulting in a decreased n-6:n-3 fatty acid ratio (FAR) in the tissue. In addition, feeding the HLO diet upregulated the expression of PPAR-γ (P < 0.05) but downregulated the expression of SCD (P < 0.05) in the adipose tissue. The results of the present study show that LO can be safely incorporated in the diets of goats to enrich goat meat with potential health beneficial FA (i.e., n-3 FA).
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影响因子：
2.4
作者：
Hajjar, Toktam;Meng, Goh Y.;Ebrahimi, Mahdi
通讯作者：
Ebrahimi, Mahdi
影响因子：
7.1
作者：
Dervishi, E.;Serrano, C.;Calvo, J. H.
通讯作者：
Calvo, J. H.
影响因子：
4.2
作者：
Deckelbaum, Richard J.;Torrejon, Claudia
通讯作者：
Torrejon, Claudia
DOI：
10.1016/j.beem.2005.07.005
发表时间：
2005-12-01
影响因子：
7.4
作者：
Al-Hasani, H;Joost, HG
通讯作者：
Joost, HG
影响因子：
7
作者：
Givens, DI
通讯作者：
Givens, DI