Frequency specific modulation of human somatosensory cortex.

Frequency specific modulation of human somatosensory cortex.
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DOI:
10.3389/fpsyg.2011.00013
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发表时间:
2011
影响因子:
3.8
通讯作者:
Kanai R
Kanai R
中科院分区:
心理学3区
文献类型:
--
作者:
Feurra M;Paulus W;Walsh V;Kanai R

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振荡神经元活动通常是对感觉刺激的反应。然而,它们的功能角色仍然是争论的主题。探索振荡神经活动的作用的一种方法是以生物学上相关的频率向皮层传递交流电,并检查这种刺激是否影响感知和认知。在这项研究中,我们测试了经颅交流电刺激(tACS)对初级体感皮层(SI)是否能以频率依赖的方式引起人类的触觉。我们在2到70 Hz的频带范围内测试了tACS在SI上的有效性。我们的研究结果表明,在α(10-14赫兹)和高γ(52-70赫兹)频率范围内的刺激会在对侧手产生触觉。β(16-20赫兹)刺激的效果也较弱。这些发现强调了有效tACS对SI的频率依赖性,其有效频率与之前在触觉感知的脑电图/脑磁图研究中观察到的频率相对应。我们目前的研究表明,tACS可以作为一种强大的在线刺激技术来揭示振荡脑活动的因果作用。
Oscillatory neuronal activities are commonly observed in response to sensory stimulation. However, their functional roles are still the subject of debate. One-way to probe the roles of oscillatory neural activities is to deliver alternating current to the cortex at biologically relevant frequencies and examine whether such stimulation influences perception and cognition. In this study, we tested whether transcranial alternating current stimulation (tACS) over the primary somatosensory cortex (SI) could elicit tactile sensations in humans in a frequency-dependent manner. We tested the effectiveness of tACS over SI at frequency bands ranging from 2 to 70 Hz. Our results show that stimulation in alpha (10–14 Hz) and high gamma (52–70 Hz) frequency range produces a tactile sensation in the contralateral hand. A weaker effect was also observed for beta (16–20 Hz) stimulation. These findings highlight the frequency dependency of effective tACS over SI with the effective frequencies corresponding to those observed in previous electroencephalography/magnetoencephalography studies of tactile perception. Our present study suggests that tACS could be used as a powerful online stimulation technique to reveal the causal roles of oscillatory brain activities.
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