Bacterial vaginosis is associated with uterine cervical human papillomavirus infection: a meta-analysis.
Bacterial vaginosis is associated with uterine cervical human papillomavirus infection: a meta-analysis.
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DOI：
10.1186/1471-2334-11-10
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发表时间：
2011-01-11
影响因子：
3.7
通讯作者：
Broeck DV
中科院分区：
文献类型：
--
作者：
Gillet E;Meys JF;Verstraelen H;Bosire C;De Sutter P;Temmerman M;Broeck DV
细菌性阴道病 (BV) 是一种阴道菌群改变，涉及乳酸杆菌减少和厌氧菌占主导地位，是育龄妇女阴道不适的最常见原因之一。众所周知，细菌性阴道炎会影响某些生殖器感染的发生。然而，BV 与宫颈人乳头瘤病毒 (HPV) 感染之间的关联在各项研究中并不一致。对已发表研究进行荟萃分析的目的是澄清和总结已发表的有关 BV 与宫颈 HPV 感染相关程度的文献。截至 2009 年 12 月，我们对 Medline 和 Web of Science 进行了系统性检索，寻找符合条件的出版物。根据纳入和排除标准选择文章。在测试研究的异质性后，使用随机效应模型进行荟萃分析。选择了 12 项符合条件的研究来审查 BV 和 HPV 之间的关联，总共包括 6,372 名女性。 BV 的汇总患病率为 32%。总体估计比值比 (OR) 显示 BV 与宫颈 HPV 感染之间呈正相关（OR，1.43；95% 置信区间，1.11-1.84）。对现有文献的荟萃分析表明 BV 与宫颈 HPV 感染之间呈正相关。
Bacterial vaginosis (BV), an alteration of vaginal flora involving a decrease in Lactobacilli and predominance of anaerobic bacteria, is among the most common cause of vaginal complaints for women of childbearing age. It is well known that BV has an influence in acquisition of certain genital infections. However, association between BV and cervical human papillomavirus (HPV) infection has been inconsistent among studies. The objective of this meta-analysis of published studies is to clarify and summarize published literature on the extent to which BV is associated with cervical HPV infection. Medline and Web of Science were systematically searched for eligible publications until December 2009. Articles were selected based on inclusion and exclusion criteria. After testing heterogeneity of studies, meta-analysis was performed using random effect model. Twelve eligible studies were selected to review the association between BV and HPV, including a total of 6,372 women. The pooled prevalence of BV was 32%. The overall estimated odds ratio (OR) showed a positive association between BV and cervical HPV infection (OR, 1.43; 95% confidence interval, 1.11-1.84). This meta-analysis of available literature resulted in a positive association between BV and uterine cervical HPV infection.
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影响因子：
11.8
作者：
Cherpes, TL;Melan, MA;Hillier, SL
通讯作者：
Hillier, SL
影响因子：
9.4
作者：
BRISELDEN, AM;MONCLA, BJ;HILLIER, SL
通讯作者：
HILLIER, SL
影响因子：
1.3
作者：
Discacciati, MG;Simoes, JA;Montemor, EBL
通讯作者：
Montemor, EBL
DOI：
10.1016/0197-2456(86)90046-2
发表时间：
1986-09-01
期刊：
CONTROLLED CLINICAL TRIALS
影响因子：
--
作者：
DERSIMONIAN, R;LAIRD, N
通讯作者：
LAIRD, N
影响因子：
3.1
作者：
Cherpes, Thomas L.;Hillier, Sharon L.;Krohn, Marijane A.
通讯作者：
Krohn, Marijane A.