Hair cortisol levels, psychological stress and psychopathological symptoms as predictors of postpartum depression.
Hair cortisol levels, psychological stress and psychopathological symptoms as predictors of postpartum depression.
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头发皮质醇水平，心理压力和心理病理学症状是产后抑郁症的预测指标。
DOI：
10.1371/journal.pone.0182817
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发表时间：
2017
期刊：
影响因子：
3.7
通讯作者：
Peralta-Ramirez MI
中科院分区：
文献类型：
--
作者：
Caparros-Gonzalez RA;Romero-Gonzalez B;Strivens-Vilchez H;Gonzalez-Perez R;Martinez-Augustin O;Peralta-Ramirez MI
产后抑郁症影响着大量的妇女，并产生有害的后果。了解怀孕期间与产后抑郁症相关的因素有助于预防。虽然有证据表明产后抑郁症的行为或心理预测因素，但缺乏生物预测因素的证据。本研究的目的是分析社会人口学，产科，心理变量沿着头发皮质醇水平在怀孕的第一，第二，第三个三个月，可以预测产后抑郁症症状。44名孕妇的样本进行了评估，在3个孕期和产后期间使用心理问卷和头发皮质醇水平。参与者被分为两组：一组有产后抑郁症状，一组没有产后抑郁症状。结果显示，在孕早期，SCL-90-R的躯体化分量表在组间存在显著的正差异（p <0.05）。在妊娠中期，躯体化、抑郁、焦虑和GSI分量表存在显著差异（p <0.05）。在第三个三个月的显着差异，发现两组之间的怀孕特定的压力。我们发现，在第一和第三个三个月的头发皮质醇水平组之间的显着的积极差异。头发皮质醇水平对产后抑郁症状的预测力为21.7%。总之，我们的研究提供了证据表明，精神病理学症状，妊娠特异性压力和头发皮质醇水平可以预测产后抑郁症症状在怀孕期间的不同时间点。这些发现可以应用于未来的研究，并改善临床环境中的孕产妇护理。
Postpartum depression affects a huge number of women and has detrimental consequences. Knowing the factors associated with postpartum depression during pregnancy can help its prevention. Although there is evidence surrounding behavioral or psychological predictors of postpartum depression, there is a lack of evidence of biological forecasters. The aim of this study was to analyze the sociodemographic, obstetric, and psychological variables along with hair cortisol levels during the first, second, and third trimesters of pregnancy that could predict postpartum depression symptoms. A sample of 44 pregnant women was assessed during 3 trimesters of pregnancy and the postpartum period using psychological questionnaires and hair cortisol levels. Participants were divided into 2 groups: a group with postpartum depression symptoms and a group with no postpartum depression symptoms. Results showed significant positive differences between groups in the first trimester regarding the Somatization subscale of the SCL-90-R (p < .05). In the second trimester, significant differences were found in the Somatization, Depression, Anxiety, and GSI subscales (p < .05). In the third trimester significant differences between both groups were found regarding pregnancy-specific stress. We found significant positive differences between groups regarding hair cortisol levels in the first and the third trimester. Hair cortisol levels could predict 21.7% of the variance of postpartum depression symptoms. In conclusion, our study provided evidence that psychopathological symptoms, pregnancy-specific stress, and hair cortisol levels can predict postpartum depression symptoms at different time-points during pregnancy. These findings can be applied in future studies and improve maternal care in clinical settings.
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影响因子：
5
作者：
COHEN, S;KAMARCK, T;MERMELSTEIN, R
通讯作者：
MERMELSTEIN, R
DOI：
10.1080/02646838.2013.835039
发表时间：
2013-11-01
影响因子：
2.5
作者：
Alderdice, Fiona;Ayers, Susan;Walsh, Judi
通讯作者：
Walsh, Judi
影响因子：
10.6
作者：
Bergman, Kristin;Sarkar, Pampa;Glover, Vivette;O'Connor, Thomas G.
通讯作者：
O'Connor, Thomas G.
影响因子：
3.7
作者：
Abell, Jessica G.;Stalder, Tobias;Ferrie, Jane E.;Shipley, Martin J.;Kirschbaum, Clemens;Kivimaki, Mika;Kumari, Meena
通讯作者：
Kumari, Meena
影响因子：
2.9
作者：
D'Anna-Hernandez, Kimberly L.;Ross, Randal G.;Laudenslager, Mark L.
通讯作者：
Laudenslager, Mark L.