Absorptive and expansive behaviors of poly(methyl methacrylate-co-acrylic acid) bone cement.
Absorptive and expansive behaviors of poly(methyl methacrylate-co-acrylic acid) bone cement.
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聚甲基丙烯酸甲酯-丙烯酸共聚骨水泥的吸收和膨胀行为
DOI：
10.1016/j.colsurfb.2020.110848
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发表时间：
2020-02
期刊：
影响因子：
--
通讯作者：
Wu Zixiang
中科院分区：
文献类型：
--
作者：
Chen Lei;Tang Yufei;Zhao Kang;Liu Jiaxin;Bai Hao;Wu Zixiang
某些添加剂为聚甲基丙烯酸甲酯（PMMA）骨水泥提供了膨胀能力，也降低了其最高反应温度。然而，相应的改性骨水泥表现出较差的模拟体液（SBF）吸收能力和膨胀行为，另外，对SBF吸收机制和膨胀应力的变化趋势也没有进行研究。在这项研究中，一个均匀分布的聚（甲基丙烯酸甲酯-丙烯酸）[P（MMA-AA）]微球形成有利于SBF向内部输送的微通道，使骨水泥在固化前的吸收能力和膨胀行为增强，最大平衡吸收率和膨胀率分别达到27.3%和26.3%，AA含量为50%时，此外，膨胀行为引起的膨胀应力在0 ~ 2590 s期间逐渐增大，在2590 ~ 2900 s期间急剧上升，最后达到最大值82.1 MPa。此外，通过控制P（MMA-AA）骨水泥中AA的含量，可获得最大值内的膨胀应力。P（MMA-AA）骨水泥具有上述特点，在关节成形术、椎体成形术、关节置换术、骨螺钉、牙科等方面具有良好的应用前景。
Some additives had provided the expansion capacity to the polymethylmethacrylate (PMMA) bone cement and also reduced its maximum reaction temperature. However, the corresponding modified bone cement displayed inferior simulated body fluid (SBF) absorption capacity and expansion behavior, the mechanism of SBF absorption and the trend of expansion stress were ignored additionally. In this study, a homogeneous distribution of poly (methyl methacrylate-co-acrylic acid) [P(MMA-AA)] microspheres led to the formation of microchannels that favored the delivery of SBF to the interior, causing an increased absorption capacity and enhanced expansion behavior before solidification of the bone cement, with the maximum equilibrium absorption ratio and the expansion ratio reaching 27.3 % and 26.3 %, respectively, at an AA content of 50 %. In addition, the expansion stress induced by the expansion behavior experienced a gradual increase from the 0 s to 2590s, followed by a sharp climbed in a short period ranging from 2590s to 2900s, finally reaching maximum stress of 82.1 MPa. Furthermore, the expansion stress within the maximum value could be obtained by controlling the AA content in the P(MMA-AA) bone cement. With the above characteristics, the prepared P(MMA-AA) bone cement has potential applications as a filling and adhesive material in arthroplasties, vertebroplasties, joint replacements, bone screws, and dentistry.
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影响因子：
2.4
作者：
Turner, CH;Rho, J;Pharr, GM
通讯作者：
Pharr, GM
影响因子：
3
作者：
Cousineau, N;McDowell, I;Hébert, P
通讯作者：
Hébert, P
DOI：
10.1039/c3tb20608d
发表时间：
2013-07
期刊：
Journal of materials chemistry. B
影响因子：
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作者：
Chao Fang;Fei Hua;Yang Cong;Jun Fu;Yajun Cheng
通讯作者：
Chao Fang;Fei Hua;Yang Cong;Jun Fu;Yajun Cheng
DOI：
10.1002/ajpa.20155
发表时间：
2004-01-01
期刊：
YEARBOOK OF PHYSICAL ANTHROPOLOGY, VOL 47
影响因子：
--
作者：
Pearson, Osbjorn M.;Lieberman, Daniel E.
通讯作者：
Lieberman, Daniel E.
影响因子：
4.6
作者：
J.J Martinez-Vega;H. Trumel;J. Gacougnolle
通讯作者：
J.J Martinez-Vega;H. Trumel;J. Gacougnolle