Fabrication of Amine-Modified Magnetite-Electrochemically Reduced Graphene Oxide Nanocomposite Modified Glassy Carbon Electrode for Sensitive Dopamine Determination.
Fabrication of Amine-Modified Magnetite-Electrochemically Reduced Graphene Oxide Nanocomposite Modified Glassy Carbon Electrode for Sensitive Dopamine Determination.
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DOI：
10.3390/nano8040194
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发表时间：
2018-03-27
期刊：
影响因子：
--
通讯作者：
Liang J
中科院分区：
文献类型：
--
作者：
He Q;Liu J;Liu X;Li G;Chen D;Deng P;Liang J
制备了氨基修饰的磁铁矿（NH 2-Fe 3 O 4）/还原氧化石墨烯纳米复合修饰玻碳电极（NH 2-Fe 3 O 4/RGO/GCEs），并用于多巴胺（DA）的灵敏检测。采用滴注法和电化学还原法制备了NH 2-Fe 3 O 4/RGO/GCE。采用扫描电子显微镜（SEM）、透射电子显微镜（TEM）、X射线衍射（XRD）和傅里叶变换红外光谱（FTIR）对NH 2-Fe 3 O 4纳米粒子（NPs）、还原氧化石墨烯（RGO）片和NH 2-Fe 3 O 4/RGO纳米复合材料的表面形貌、微观结构和化学组成进行了表征。在磷酸盐缓冲溶液（PBS）中，用循环伏安法（CV）研究了DA在裸电极和修饰电极上的电化学行为。与裸电极和RGO/GCE相比，NH 2-Fe 3 O 4/RGO/GCE上的氧化峰电流（ipa）显著增加，这是由于NH 2-Fe 3 O 4纳米粒子与RGO片之间的协同效应。在1 × 10−8 mol/L ~ 1 × 10−7 mol/L、1 × 10 −7 mol/L ~ 1 × 10−6 mol/L和1 × 10 − 6 mol/L ~ 1 × 10−5 mol/L范围内，氧化峰电流（ipa）与DA浓度呈线性关系。检出限为（4.0 ± 0.36）×10−9 mol/L（S/N = 3）。抗坏血酸（AA）和尿酸（UA）共存时，DA的响应峰电流几乎不受干扰。该方法用于盐酸多巴胺注射液的检测，结果令人满意。NH_2-Fe_3O_4/RGO/GCEs具有成本低、操作简便、选择性好、灵敏度高等优点，在各种真实的样品中DA的检测中具有广阔的应用前景。
Amine-modified magnetite (NH2–Fe3O4)/reduced graphene oxide nanocomposite modified glassy carbon electrodes (NH2–Fe3O4/RGO/GCEs) were developed for the sensitive detection of dopamine (DA). The NH2-Fe3O4/RGO/GCEs were fabricated using a drop-casting method followed by an electrochemical reduction process. The surface morphologies, microstructure and chemical compositions of the NH2–Fe3O4 nanoparticles (NPs), reduced graphene oxide (RGO) sheets and NH2–Fe3O4/RGO nanocomposites were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-Ray diffraction (XRD) and Fourier-transform infrared (FTIR) spectroscopy. The electrochemical behaviors of DA on the bare and modified GCEs were investigated in phosphate buffer solution (PBS) by cyclic voltammetry (CV). Compared with bare electrode and RGO/GCE, the oxidation peak current (ipa) on the NH2–Fe3O4/RGO/GCE increase significantly, owing to the synergistic effect between NH2–Fe3O4 NPs and RGO sheets. The oxidation peak currents (ipa) increase linearly with the concentrations of DA in the range of 1 × 10−8 mol/L – 1 × 10−7 mol/L, 1 × 10−7 mol/L – 1 × 10−6 mol/L and 1 × 10−6 mol/L – 1 × 10−5 mol/L. The detection limit is (4.0 ± 0.36) ×10−9 mol/L (S/N = 3). Moreover, the response peak currents of DA were hardly interfered with the coexistence of ascorbic acid (AA) and uric acid (UA). The proposed NH2–Fe3O4/RGO/GCE is successfully applied to the detection of dopamine hydrochloride injections with satisfactory results. Together with low cost, facile operation, good selectivity and high sensitivity, the NH2–Fe3O4/RGO/GCEs have tremendous prospects for the detection of DA in various real samples.
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影响因子：
3.7
作者：
Chen, Rufen;Song, Guoqiang;Wei, Yu
通讯作者：
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15
作者：
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通讯作者：
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影响因子：
4.2
作者：
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