Sleep duration and metabolic syndrome in adult populations: a meta-analysis of observational studies.

Sleep duration and metabolic syndrome in adult populations: a meta-analysis of observational studies.
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DOI:
10.1038/nutd.2013.8
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发表时间:
2013-05-13
影响因子:
6.1
通讯作者:
Choi, W-S
Choi, W-S
中科院分区:
医学2区
文献类型:
--
作者:
Ju, S-Y;Choi, W-S

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流行病学研究已经反复调查了睡眠时间和代谢综合征之间的关系。然而,结果却不一致。本荟萃分析旨在总结评价这一点的横断面和前瞻性队列研究的现有证据。通过系统检索PubMed、科克伦CENTRAL、EMBASE和PsycINFO数据库(截至2012年11月,无语言限制)确定相关研究。我们确定了12个横断面研究,76 027名参与者,包括14 404例代谢综合征,和3个队列研究,2055名参与者和283例代谢综合征的事件。对于短睡眠时间(<5 ~ 6 h),OR值为1.27(12项横断面研究中的95%置信区间(CI)=1.10-1.48,I2=75.5%)和1.62(95%CI =0.74-3.55,I2=71.4%);对于长时间睡眠(>8 ~ 10 h),11项横断面研究的OR为1.23(95%CI =1.02-1.49,I2=75.8%),2项队列研究的OR为1.62(95%CI =0.86-3.04,I2=0.0%)。短时间和长时间的睡眠是增加代谢综合征风险的危险行为,因此具有重要的公共卫生意义,因为睡眠习惯可以接受行为干预。现有的数据是稀疏的,需要进一步的研究,特别是纵向研究,以促进更好地了解这些协会。
Epidemiological studies have repeatedly investigated the association between sleep duration and metabolic syndrome. However, the results have been inconsistent. This meta-analysis aimed to summarize the current evidence from cross-sectional and prospective cohort studies that evaluated this. Relevant studies were identified by systematically searching the PubMed, Cochrane CENTRAL, EMBASE and PsycINFO databases through November 2012 without language restriction. We identified 12 cross-sectional studies with 76 027 participants including 14 404 cases of metabolic syndrome, and 3 cohort studies with 2055 participants and 283 incident cases of metabolic syndrome. For short sleep durations (<5 to 6 h), the odds ratios (OR) was 1.27 (95% confidence interval (CI)=1.10–1.48, I2=75.5%) in the 12 cross-sectional studies and 1.62 (95% CI=0.74–3.55, I2=71.4%) in the 3 cohort studies; for long sleep durations (>8 to 10 h), the OR was 1.23 (95% CI=1.02–1.49, I2=75.8%) in the 11 cross-sectional studies and 1.62 (95% CI=0.86–3.04, I2=0.0%) in the 2 cohort studies. Short and long sleep durations are risky behaviors for increasing the risk of metabolic syndrome and thus have important public health implications, as sleep habits are amenable to behavioral interventions. The available data are sparse, and further studies, especially longitudinal studies, are needed to facilitate a better understanding of these associations.
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