A comparison of retinal nerve fiber layer (RNFL) thickness obtained with frequency and time domain optical coherence tomography (OCT).

A comparison of retinal nerve fiber layer (RNFL) thickness obtained with frequency and time domain optical coherence tomography (OCT).
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DOI:
10.1364/oe.17.003997
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发表时间:
2009-03-02
期刊:
影响因子:
3.8
通讯作者:
Liebmann JM
Liebmann JM
中科院分区:
物理与天体物理2区
文献类型:
--
作者:
Hood DC;Raza AS;Kay KY;Sandler SF;Xin D;Ritch R;Liebmann JM

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为了诊断青光眼和视网膜神经节细胞/视神经的其他疾病,常规地用光学相干断层扫描测量视网膜神经纤维层(RNFL)的厚度。直到最近,这些OCT测量几乎都是使用来自单一制造商的时域OCT(tdOCT)机器进行的。最近,已经出现了许多基于改进的频域OCT技术(fdOCT)的OCT机器。我们比较了使用新的fdOCT机器和旧的tdOCT机器进行的测量。结果具有可比性。更重要的是,我们了解到,决定不同机器的结果是否具有可比性的关键因素是用于分割RNFL厚度的算法,而不是OCT的类型。
To diagnose glaucoma and other diseases of the retinal ganglion cell/ optic nerve, the thickness of the retinal nerve fiber layer (RNFL) is routinely measured with optical coherence tomography. Until recently, these OCT measurements were made almost exclusively with a time domain OCT (tdOCT) machine from a single manufacturer. Recently, a number of OCT machines, based upon an improved frequency domain OCT technology (fdOCT), have appeared. We compared measurements made using a new fdOCT machine to those from the older tdOCT machine. The results were comparable. More importantly, we learned that the key factor determining whether results from different machines will be comparable is the algorithm used to segment RNFL thickness, not the type of OCT.
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发表时间: 2007-11-01
影响因子: 17.8
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