Deciphering the Formulation Secret Underlying Chinese Huo-Clearing Herbal Drink.
Deciphering the Formulation Secret Underlying Chinese Huo-Clearing Herbal Drink.
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DOI：
10.3389/fphar.2021.654699
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发表时间：
2021
影响因子：
5.6
通讯作者：
Hu X
中科院分区：
文献类型：
--
作者：
Wang J;Zhou B;Hu X;Dong S;Hong M;Wang J;Chen J;Zhang J;Zhang Q;Li X;Shikov AN;Hu S;Hu X
草药茶或草药饮料是在世界各地的许多文化中流行的传统饮料。在中国传统医学中，一种含有不同类型药用植物的草药饮料被认为可以减少“上火”，或过多的身体热量，这是一种次优健康状态。虽然它被广泛接受，并有一个非常大的市场，草药饮料的基础科学仍然难以捉摸。通过研究一组草药的饮料，包括'甘'（甘草菲施。Ex DC.），菊（Dendranthema morifolium（Ramat.）Tzvelev）、布谷（Microcos paniculata L.）'锦'（EscherajaponicaThunb.）'夏'（夏枯草），和鸡蛋花'Ji'，长期术语通过一些促炎标志物与现代免疫学的炎症有关。体外研究表明，Ju和Jin单独或与Gan协同降低细胞炎症。在所有的中药中，只有甘草对补的细胞毒性有剂量依赖性的解毒作用。对桔、甘、金、甘配伍减伤活的协同作用进行了体内试验。两种组合均表现出较低的血液中中性粒细胞、单核细胞和CD 4 +/CD 8+比率以及炎性细胞因子百分比。此外，组合组的体重比使用单味中药的处理更稳定。古老的传统东方方法与西方科学物流相结合，导致了不同草药的配方成为一种混合物，用于解毒和协同作用。
Herbal teas or herbal drinks are traditional beverages that are prevalent in many cultures around the world. In Traditional Chinese Medicine, an herbal drink infused with different types of medicinal plants is believed to reduce the ‘Shang Huo’, or excessive body heat, a status of sub-optimal health. Although it is widely accepted and has a very large market, the underlying science for herbal drinks remains elusive. By studying a group of herbs for drinks, including ‘Gan’ (Glycyrrhiza uralensis Fisch. Ex DC.), ‘Ju’ (Dendranthema morifolium (Ramat.) Tzvelev), ‘Bu’ (Microcos paniculata L.), ‘Jin’ (Lonicera japonica Thunb.), ‘Xia’ (Prunella vulgaris L.), and ‘Ji’ (Plumeria rubra L.), the long-term jargon is connected with the inflammation of modern immunology through a few pro-inflammatory markers. In vitro studies have indicated that cellular inflammation is lowered by Ju and Jin either individually or synergistically with Gan. Among all herbs, only Gan detoxicated cellular toxicity of Bu in a dose dependent manner. The synergistic formulation of Ju and Gan, or Jin and Gan, in a reduction of Shang Huo, was tested in vivo. Both combinations exhibited a lower percentage of neutrophils, monocytes, and CD4+/CD8+ ratio in the blood, as well as inflammatory cytokines. Furthermore, body weight in the combinatory groups was more stable than treatments using single herbs. The combination of old traditional oriental methods with Western science logistics, has resulted in the formulation of different herbs into one concoction for the use of detoxification and synergism.
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影响因子：
5.6
作者：
Gu S;Pei J
通讯作者：
Pei J
DOI：
10.1080/09637480601108307
发表时间：
2007-03-01
影响因子：
3.9
作者：
Kulisic, Tea;Krisko, Anita;Pifat, Greta
通讯作者：
Pifat, Greta
影响因子：
0.9
作者：
van Heerden, Stefanus G.;Hardie, Ailsa G.
通讯作者：
Hardie, Ailsa G.
影响因子：
4.1
作者：
Kieling, Dirlei Diedrich;Prudencio, Sandra Helena
通讯作者：
Prudencio, Sandra Helena
影响因子：
13.3
作者：
Panossian AG;Efferth T;Shikov AN;Pozharitskaya ON;Kuchta K;Mukherjee PK;Banerjee S;Heinrich M;Wu W;Guo DA;Wagner H
通讯作者：
Wagner H