Comparison of diet, muscle strength, steps per day and symptoms in people with HIV and HIV-negative peers.
Comparison of diet, muscle strength, steps per day and symptoms in people with HIV and HIV-negative peers.
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DOI：
10.1002/nur.22202
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发表时间：
2022-03
影响因子：
2
通讯作者：
Webel A
中科院分区：
文献类型：
--
作者：
Davey CH;Trinh V;Schexnayder J;Longenecker CT;Webel A
艾滋病毒感染者（PWH）经常出现与不良临床结果相关的症状。我们对一项观察性研究的数据进行了二次分析，以检查饮食、肌肉力量或身体活动是否与PWH及其未感染hiv的同伴的症状相关。191名年龄和种族相似的个体（105名PWH和86名HIV未感染者）被纳入研究。使用患者报告结果测量信息系统（promise -29）问卷检查症状，得分越低表明功能越好或症状越少。通过24小时饮食回顾获得健康饮食指数总分和每天碳水化合物、含糖甜饮料、酒精和纤维的摄入量。用测力计测定肌肉力量。通过7天的活动记录仪检查每天的步数。采用线性回归分析确定症状与饮食、肌肉力量和每日步数之间的关系。参与者的平均年龄为54岁，83%为非裔美国人，58%为男性。在PWH中，不健康的饮食、纤维摄入量和肌肉力量与较差的身体功能有关；每天多走几步与疲劳有关；每天较少的碳水化合物摄入与更多的疼痛有关。未感染艾滋病毒的个体表现出每天较少的步数与较差的身体功能和更多的疼痛，较少的碳水化合物摄入和更多的睡眠障碍之间的联系。饮食、肌肉力量和每日步数之间的关系因HIV感染状况而异。
People with HIV (PWH) experience a high frequency of symptoms that are associated with poor clinical outcomes. We conducted a secondary analysis of data from an observational study to examine whether diet, muscle strength, or physical activity were associated with symptoms among PWH and their HIV-uninfected peers. One-hundred ninety-one individuals (105 PWH and 86 HIV uninfected) with similar age and race were included. Symptoms were examined using the Patient-Reported Outcomes Measurement Information System (PROMIS-29) questionnaire, for which lower scores indicate higher function or fewer symptoms. The total healthy eating index score and carbohydrates, sugar sweet beverages, alcohol, and fiber consumption per day were obtained through 24-hour dietary recalls. A dynamometer was used to determine muscle strength. Steps per day were examined through 7 days of actigraphy. Linear regression analyses were used to determine the relationship between symptoms and diet, muscle strength, and steps per day. Participants were, on average, 54 years, 83% were African American, and 58% were male. In PWH, less healthy eating, fiber intake, and muscle strength were associated with poorer physical function; more steps per day were associated with fatigue; less daily carbohydrate consumption was associated with more pain. HIV-uninfected individuals demonstrated an association between fewer steps per day and poorer physical function and more pain, and less carbohydrate intake and more sleep disturbance. The relationships between diet, muscle strength and steps per day PROMIS-29 health domains differed by HIV status.
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DOI：
10.1111/tmi.12852
发表时间：
2017-05
期刊：
Tropical medicine & international health : TM & IH
影响因子：
--
作者：
Bernard C;Dabis F;de Rekeneire N
通讯作者：
de Rekeneire N
影响因子：
9.3
作者：
Bales, Connie W.;Starr, Kathryn N. Porter
通讯作者：
Starr, Kathryn N. Porter
影响因子：
2.8
作者：
Dianatinasab, Mostafa;Fararouei, Mohammad;AminiLari, Mahmood
通讯作者：
AminiLari, Mahmood
影响因子：
4.7
作者：
Kaleth, Anthony S.;Slaven, James E.;Ang, Dennis C.
通讯作者：
Ang, Dennis C.
影响因子：
9.3
作者：
Hagen KB;Dagfinrud H;Moe RH;Østerås N;Kjeken I;Grotle M;Smedslund G
通讯作者：
Smedslund G