Cyclebase.org--a comprehensive multi-organism online database of cell-cycle experiments.
Cyclebase.org--a comprehensive multi-organism online database of cell-cycle experiments.
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DOI:
10.1093/nar/gkm729
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发表时间:
2008-01
影响因子:
14.9
通讯作者:
Jensen TS
中科院分区:
文献类型:
--
作者:
Gauthier NP;Larsen ME;Wernersson R;de Lichtenberg U;Jensen LJ;Brunak S;Jensen TS
The past decade has seen the publication of a large number of cell-cycle microarray studies and many more are in the pipeline. However, data from these experiments are not easy to access, combine and evaluate. We have developed a centralized database with an easy-to-use interface, Cyclebase.org, for viewing and downloading these data. The user interface facilitates searches for genes of interest as well as downloads of genome-wide results. Individual genes are displayed with graphs of expression profiles throughout the cell cycle from all available experiments. These expression profiles are normalized to a common timescale to enable inspection of the combined experimental evidence. Furthermore, state-of-the-art computational analyses provide key information on both individual experiments and combined datasets such as whether or not a gene is periodically expressed and, if so, the time of peak expression. Cyclebase is available at http://www.cyclebase.org.
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