Lack of cholinergic control in feedback regulation of pancreatic secretion in the rat.
Lack of cholinergic control in feedback regulation of pancreatic secretion in the rat.
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大鼠胰腺分泌反馈调节缺乏胆碱能控制。
DOI：
10.1016/0016-5085(90)90836-p
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发表时间：
1990
期刊：
影响因子：
29.4
通讯作者：
Green,GM
中科院分区：
文献类型：
--
作者：
Guan,D;Ohta,H;Tawil,T;Spannagel,AW;Liddle,RA;Green,GM
The effect of atropine (100 μg/kg/h, i.v.) on plasma cholecystokinin and pancreatic secretion during diversion of bile and pancreatic juice from the intestine was studied in 8 conscious rats equipped with jugular vein, pancreatic, biliary, and duodenal cannulas, and with pyloric ligation and gastric drainage. Diversion of bile and pancreatic juice to the exterior for 4 h significantly increased pancreatic protein and fluid secretion. Atropine delayed the pancreatic response to diversion, but during 4 h of diversion, neither total nor incremental pancreatic protein or fluid secretion was inhibited by atropine. Plasma cholecystokinin levels were elevated after diverting bile and pancreatic juice and were not significantly reduced by atropine (23.0 ± 6.6 pM vs. 16.0 ± 3.9 pM at 1.5 h and 17.3 ± 5.4 pM vs. 13.1 ± 2.9 pM at 4 h after bile and pancreatic juice diversion; atropine-treated vs. controls, respectively). These results indicate that cholinergic nerves play no important role in feedback regulation of cholecystokinin release and that the previously reported suppressive effect of atropine on the pancreatic response to diversion of bile and pancreatic juice from the intestine was secondary to inhibition of gastric secretion.
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生理条件下的膜运输和水解酶。
DOI：
--
发表时间：
1987
期刊：
影响因子：
--
作者：
A. Ugolev
通讯作者：
A. Ugolev
大鼠胰腺酶分泌响应食物蛋白质摄入的阿托品非敏感反馈调节机制。
DOI：
--
发表时间：
1987
期刊：
Journal of NutriLife
影响因子：
--
作者：
T. Fushiki;S. Fukuoka;H. Kajiura;K. Iwai
通讯作者：
K. Iwai
胃分泌在清醒大鼠转移后胰腺分泌过多中的作用。
DOI：
--
发表时间：
1982
期刊：
Journal of Physiology
影响因子：
--
作者：
A. Noda;D. F. Magee;H. Sarles
通讯作者：
H. Sarles
阿托品对大鼠胰腺对胰蛋白酶抑制剂和蛋白质分泌反应的影响。
影响因子：
--
作者：
V. H. Levan;G. Green
通讯作者：
G. Green
DOI：
--
发表时间：
1989
期刊：
The FASEB Journal
影响因子：
--
作者：
T. Fushiki;K. Iwai
通讯作者：
K. Iwai