The coagulation system in host defense.
The coagulation system in host defense.
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DOI:
10.1002/rth2.12109
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发表时间:
2018-07
影响因子:
4.6
通讯作者:
Antoniak S
中科院分区:
文献类型:
--
作者:
Antoniak S
The blood coagulation system and immune system of higher organisms are thought to have a common ancestral origin. During infections, the blood coagulation system is activated and components of the hemostatic system are directly involved in the immune response and immune system modulations. The current view is that the activation of coagulation is beneficial for infections with bacteria and viruses. It limits pathogen dissemination and supports pathogen killing and tissue repair. On the other hand, over‐activation can lead to thrombosis with subsequent depletion of hemostatic factors and secondary bleeding. This review will summarize the current knowledge on blood coagulation and pathogen infection with focus on most recent studies of the role of the different parts of the blood coagulation system in selected bacterial and viral infections.
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影响因子:
6.7
作者:
Antoniak S;Sparkenbaugh E;Pawlinski R
通讯作者:
Pawlinski R
影响因子:
--
作者:
Bhattacharya S;Ploplis VA;Castellino FJ
通讯作者:
Castellino FJ
DOI:
10.1111/jth.13307
发表时间:
2016-06
期刊:
Journal of thrombosis and haemostasis : JTH
影响因子:
--
作者:
Antoniak S;Tatsumi K;Hisada Y;Milner JJ;Neidich SD;Shaver CM;Pawlinski R;Beck MA;Bastarache JA;Mackman N
通讯作者:
Mackman N
影响因子:
3.2
作者:
Flick, MJ;Du, XL;Degen, JL
通讯作者:
Degen, JL
影响因子:
11.8
作者:
Boyer Chammard T;Schepers K;Breurec S;Messiaen T;Destrem AL;Mahevas M;Soulillou A;Janaud L;Curlier E;Herrmann-Storck C;Hoen B
通讯作者:
Hoen B