Recent advances in nanoparticle-based Förster resonance energy transfer for biosensing, molecular imaging and drug release profiling.
Recent advances in nanoparticle-based Förster resonance energy transfer for biosensing, molecular imaging and drug release profiling.
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基于纳米颗粒的Förster共振能量转移的最新进展用于生物传感，分子成像和药物释放分析。
DOI：
10.3390/ijms131216598
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发表时间：
2012-12-05
影响因子：
5.6
通讯作者：
Lo LW
中科院分区：
文献类型：
--
作者：
Chen NT;Cheng SH;Liu CP;Souris JS;Chen CT;Mou CY;Lo LW
Förster resonance energy transfer (FRET) may be regarded as a “smart” technology in the design of fluorescence probes for biological sensing and imaging. Recently, a variety of nanoparticles that include quantum dots, gold nanoparticles, polymer, mesoporous silica nanoparticles and upconversion nanoparticles have been employed to modulate FRET. Researchers have developed a number of “visible” and “activatable” FRET probes sensitive to specific changes in the biological environment that are especially attractive from the biomedical point of view. This article reviews recent progress in bringing these nanoparticle-modulated energy transfer schemes to fruition for applications in biosensing, molecular imaging and drug delivery.
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