Recent advances in neuroimaging biomarkers in geriatric psychiatry.
Recent advances in neuroimaging biomarkers in geriatric psychiatry.
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DOI：
10.1007/s11920-013-0360-9
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发表时间：
2013-06
影响因子：
6.7
通讯作者：
Aizenstein, Howard J.
中科院分区：
文献类型：
--
作者：
Khandai, Abhisek C.;Aizenstein, Howard J.
关键词：
Neuroimaging, both structural and functional, serve as useful adjuncts to clinical assessment, and can provide objective, reliable means of assessing disease presence and process in the aging population. In the following review we briefly explain current imaging methodologies. Then, we analyze recent developments in developing neuroimaging biomarkers for two highly prevalent disorders in the elderly population- Alzheimer's disease (AD) and late-life depression (LLD). In AD, efforts are focused on early diagnosis through in vivo visualization of disease pathophysiology. In LLD, recent imaging evidence supports the role of white matter ischemic changes in the pathogenesis of depression in the elderly, the “vascular hypothesis.” Finally, we discuss potential roles for neuroimaging biomarkers in geriatric psychiatry in the future.
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DOI：
10.1176/appi.ajp.2011.10060853
发表时间：
2011-10
期刊：
The American journal of psychiatry
影响因子：
--
作者：
Aizenstein HJ;Andreescu C;Edelman KL;Cochran JL;Price J;Butters MA;Karp J;Patel M;Reynolds CF 3rd
通讯作者：
Reynolds CF 3rd
DOI：
10.1097/jgp.0b013e318211069a
发表时间：
2011-09
期刊：
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
影响因子：
--
作者：
Burke J;McQuoid DR;Payne ME;Steffens DC;Krishnan RR;Taylor WD
通讯作者：
Taylor WD
影响因子：
4
作者：
Forester, Brent P.;Harper, David G.;Cohen, Bruce M.
通讯作者：
Cohen, Bruce M.
影响因子：
6.6
作者：
Goveas, Joseph S.;Espeland, Mark A.;Hogan, Patricia;Dotson, Vonetta;Tarima, Sergey;Coker, Laura H.;Ockene, Judith;Brunner, Robert;Woods, Nancy F.;Wassertheil-Smoller, Sylvia;Kotchen, Jane M.;Resnick, Susan
通讯作者：
Resnick, Susan
DOI：
10.1001/jama.2010.2008
发表时间：
2011-01-19
期刊：
JAMA
影响因子：
--
作者：
Clark CM;Schneider JA;Bedell BJ;Beach TG;Bilker WB;Mintun MA;Pontecorvo MJ;Hefti F;Carpenter AP;Flitter ML;Krautkramer MJ;Kung HF;Coleman RE;Doraiswamy PM;Fleisher AS;Sabbagh MN;Sadowsky CH;Reiman EP;Zehntner SP;Skovronsky DM;AV45-A07 Study Group
通讯作者：
AV45-A07 Study Group