Researches on cognitive sequelae of burn injury: Current status and advances.
Researches on cognitive sequelae of burn injury: Current status and advances.
复制标题
烧伤认知后遗症的研究现状与进展
DOI：
10.3389/fnins.2022.1026152
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发表时间：
2022
影响因子：
4.3
通讯作者：
Yao, Zhongxiang
中科院分区：
文献类型：
--
作者：
Xie, Chenchen;Hu, Jun;Cheng, Yong;Yao, Zhongxiang
关键词：
Burn injury is a devastating disease with high incidence of disability and mortality. The cognitive dysfunctions, such as memory defect, are the main neurological sequelae influencing the life quality of burn-injured patients. The post-burn cognitive dysfunctions are related to the primary peripheral factors and the secondary cerebral inflammation, resulting in the destruction of blood-brain barrier (BBB), as is shown on Computed Tomography (CT) and magnetic resonance imaging examinations. As part of the neurovascular unit, BBB is vital to the nutrition and homeostasis of the central nervous system (CNS) and undergoes myriad alterations after burn injury, causing post-burn cognitive defects. The diagnosis and treatment of cognitive dysfunctions as burn injury sequelae are of great importance. In this review, we address the major manifestations and interventions of post-burn cognitive defects, as well as the mechanisms involved in memory defect, including neuroinflammation, destruction of BBB, and hormone imbalance.
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影响因子：
--
作者：
Ali MB;Ali MB
通讯作者：
Ali MB
影响因子：
3.9
作者：
Walrath, Travis;McMahan, Rachel H.;Idrovo, Juan-Pablo;Quillinan, Nidia;Kovacs, Elizabeth J.
通讯作者：
Kovacs, Elizabeth J.
影响因子：
2.1
作者：
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通讯作者：
Mennemeier, Mark
影响因子：
3.7
作者：
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通讯作者：
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DOI：
10.1186/cc9300
发表时间：
2010
期刊：
Critical care (London, England)
影响因子：
--
作者：
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通讯作者：
Blot S