Selection and Functionalization of Germanium Nanowires for Bio-Sensing.
Selection and Functionalization of Germanium Nanowires for Bio-Sensing.
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DOI:
10.1021/acsomega.2c04775
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发表时间:
2022-10-04
期刊:
影响因子:
4.1
通讯作者:
Sandall, Ian
中科院分区:
文献类型:
--
作者:
Laumier, Siriny;Farrow, Thomas;van Zalinge, Harm;Seravalli, Luca;Bosi, Matteo;Sandall, Ian
In this paper, we investigate the use of dielectrophoresis to align germanium nanowire arrays to realize nanowire-based diodes and their subsequent use for bio-sensing. After establishing that dielectrophoresis is a controllable and repeatable fabrication method to create devices from germanium nanowires, we use the optimum process conditions to form a series of diodes. These are subsequently functionalized with an aptamer, which is able to bind specifically to the spike protein of SARS-Cov2 and investigated as a potential sensor. We observe a linear increase in the source to drain current as the concentration of spike protein is increased from 100 fM/L to 1 nM/L.
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