Cannabis and Alcohol Co-Use and Condomless Anal Sex Among Men Who have Sex with Men Living with HIV: An Event-Level Analysis.
Cannabis and Alcohol Co-Use and Condomless Anal Sex Among Men Who have Sex with Men Living with HIV: An Event-Level Analysis.
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DOI：
10.1007/s10461-021-03228-6
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发表时间：
2021-11
影响因子：
4.4
通讯作者：
Woolf-King SE
中科院分区：
文献类型：
--
作者：
Firkey M;Sheinfil A;Ramos J;Woolf-King SE
男男性行为者（MSM）占每年艾滋病毒新诊断的三分之二以上。增加艾滋病毒传播风险的性行为与酒精和大麻使用有关。然而，关于大麻和酒精共同使用对无避孕套肛交（CAS）的影响知之甚少。本研究采用为期42天的时间轴随访访谈（N=101），探讨了HIV阳性MSM中物质使用与CAS之间的日常关联。广义估计方程（GEE）逻辑回归模型被用来检查大麻和酒精的共同使用和CAS在性事件之间的关联，同时控制研究地点，条件，坚持抗逆转录病毒治疗，性相关的酒精预期，和合作伙伴类型。参与者提供了1,052个性活动日的数据，其中60.7%涉及CAS。在638天的CAS中，9.1%不涉及任何物质，72.0%涉及大麻或酒精使用，18.9%涉及大麻和酒精共同使用。结果表明，参与CAS的几率较高的性事件中，大麻和酒精的共同使用发生（aOR = 2.98; 95% CI：1.27，6.97）与未发生药物使用的事件相比（p = .012），但当大麻和酒精共同使用与单一物质使用相比时，这种关系不再显著（aOR = 1.57; 95% CI：0.85，2.90; p = 0.15）。未来的研究应确定具体的物质使用（例如，数量）和伙伴特性（例如，中毒程度），这可能会独特地影响大麻和酒精共同使用和无避孕套性行为之间的关系。
Men who have sex with men (MSM) account for more than two thirds of new HIV diagnoses annually. Sexual behavior that increases risk for onward transmission of HIV is associated with both alcohol and cannabis use. However, little is known about the influence of cannabis and alcohol co-use on engagement in condomless anal sex (CAS). The current study explored daily associations between substance use and CAS among HIV-positive MSM using a 42-day Timeline Followback interview (N=101). Generalized estimating equation (GEE) logistic regression models were used to examine the association between cannabis and alcohol co-use and CAS at the sexual event while controlling for study site, condition, adherence to antiretroviral therapy, sex-related alcohol expectancies, and partner type. Participants provided data for 1,052 sexual activity days, 60.7% of which involved CAS. Of 638 CAS days, 9.1% involved no substances, 72.0% involved either cannabis or alcohol use, and 18.9% involved cannabis and alcohol co-use. Results indicated that the odds of engaging in CAS were higher for sexual events in which cannabis and alcohol co-use occurred (aOR = 2.98; 95% CI: 1.27, 6.97) compared to events in which no substance use occurred (p = .012), but this relationship was no longer significant when cannabis and alcohol co-use was compared to single substance use (aOR = 1.57; 95% CI: 0.85, 2.90; p = .15). Future research should identify specific substance use (e.g., quantity) and partner characteristics (e.g., level of intoxication) that may uniquely influence the relationship between cannabis and alcohol co-use and condomless sex.
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影响因子：
17.7
作者：
Green, JE;Saveanu, RV;Bornstein, RA
通讯作者：
Bornstein, RA
DOI：
10.1097/01.qai.0000230530.02212.86
发表时间：
2006-11-01
影响因子：
3.6
作者：
Drumright, Lydia N.;Little, Susan J.;Gorbach, Pamina M.
通讯作者：
Gorbach, Pamina M.
影响因子：
4.4
作者：
Boone, Melissa R.;Cook, Stephanie H.;Wilson, Patrick
通讯作者：
Wilson, Patrick
影响因子：
5
作者：
Colfax, G;Vittinghoff, E;Coates, TJ
通讯作者：
Coates, TJ
DOI：
10.1016/j.pbb.2017.08.009
发表时间：
2018-01
期刊：
Pharmacology, biochemistry, and behavior
影响因子：
--
作者：
Berry MS;Johnson MW
通讯作者：
Johnson MW