Parent Joint AB Blood Group Is Associated With Clinical Outcomes of in vitro Fertilization and Intracytoplasmic Sperm Injection Treatment in Chinese Women.
Parent Joint AB Blood Group Is Associated With Clinical Outcomes of in vitro Fertilization and Intracytoplasmic Sperm Injection Treatment in Chinese Women.
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DOI：
10.3389/fmed.2022.813781
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发表时间：
2022
影响因子：
3.9
通讯作者：
中科院分区：
文献类型：
--
作者：
许多出版物研究了血型和女性不孕症之间的关系，包括卵巢储备，复发性流产和活产。然而，缺乏文献研究联合母亲/父亲ABO血型在一个大的队列。本研究旨在探讨ABO血型夫妇组合与接受体外受精（IVF）/卵胞浆内单精子注射（ICSI）患者辅助生殖技术（ART）结局之间的相关性。这项回顾性队列研究包括30，717对在2010年至2019年期间接受IVF周期的夫妇。IVF治疗的临床结局是主要结局。对自然流产史、胚胎质量、出生性别、体重、畸形率等进行研究。两个血型组之间的基线人口统计学无差异。女性AB型血和男性AB型血的组合与生化妊娠、临床妊娠和活产率之间存在统计学显著的正相关（OR 1.36; 95%CI，1.05-1.78; P = 0.02和OR 1.31; 95%CI，1.0-1.68; P = 0.031和OR 1.28; 95%CI，1.01-1.63; P = 0.041）。两组间ABO血型差异无统计学意义（P > 0. 05），优质胚胎率、早期流产率、出生性别、出生体重、出生缺陷率差异无统计学意义（P > 0. 05）。本研究结果提示，母方交配AB血型的IVF/ICSI周期成功率高于其他血型组合。
A number of publications have examined the relation between blood group and female infertility including ovarian reserve, recurrent miscarriage, and live birth. However, there is a lack of literature investigating joint mother/father ABO blood type in a large cohort. This study aimed to investigate the association between couple combinations for ABO blood groups and assisted reproductive technology (ART) outcomes in patients undergoing in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI). This retrospective cohort study included 30,717 couples who underwent IVF cycles between 2010 and 2019. The clinical outcomes of IVF treatment were the primary outcome. History of spontaneous miscarriage, embryo quality, and birth sex, weights, defects rate were also studied. There was no difference in the baseline demographics between the blood type groups. There was a statistically significant positive association between the combination of female blood type AB and male blood type AB with biochemical pregnancy, clinical pregnancy, and live birth rate (OR 1.36; 95% CI, 1.05–1.78; P = 0.02 and OR 1.31; 95% CI, 1.0–1.68; P = 0.031 and OR 1.28; 95% CI, 1.01–1.63; P = 0.041 respectively). No statistically significant difference was observed between joint mother/father ABO blood types and high-quality embryo rate, early abortion rate, birth sex, birth weights, and birth defect rate. Our findings suggest that the success rate of IVF/ICSI cycles in parent mating AB blood type is higher than that in other blood type combination groups.
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DOI：
10.1056/nejmoa0806228
发表时间：
2009-03-19
期刊：
The New England journal of medicine
影响因子：
--
作者：
Lourenço D;Brauner R;Lin L;De Perdigo A;Weryha G;Muresan M;Boudjenah R;Guerra-Junior G;Maciel-Guerra AT;Achermann JC;McElreavey K;Bashamboo A
通讯作者：
Bashamboo A
影响因子：
1.6
作者：
Awartani K;Al Ghabshi R;Al Shankiti H;Al Dossari M;Coskun S
通讯作者：
Coskun S
ABO血型对中国女性卵巢储备功能的影响
影响因子：
6.7
作者：
Lin, Shengli;Li, Rong;Qiao, Jie
通讯作者：
Qiao, Jie
影响因子：
5.2
作者：
Fang, Lanlan;He, Jingyan;Sun, Ying-Pu
通讯作者：
Sun, Ying-Pu
影响因子：
2.6
作者：
Matalliotakis, Ioannis;Cakmak, Hakan;Arici, Aydin
通讯作者：
Arici, Aydin