Retrospective review of neurodevelopmental outcomes in infants treated for neonatal abstinence syndrome.
Retrospective review of neurodevelopmental outcomes in infants treated for neonatal abstinence syndrome.
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DOI：
10.1038/s41372-018-0088-9
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发表时间：
2018-05
期刊：
影响因子：
--
通讯作者：
Poindexter BB
中科院分区：
文献类型：
--
作者：
Merhar SL;McAllister JM;Wedig-Stevie KE;Klein AC;Meinzen-Derr J;Poindexter BB
对新生儿禁欲综合征(NAS)的发育结局知之甚少。我们假设接受NAS治疗的儿童在第三版贝利婴儿发育量表上的得分低于标准样本。我们对87名接受NAS治疗的婴儿进行了一项回顾性队列研究，并在2岁时进行了评估。接受NAS治疗的儿童在所有3个维度上的得分均显著低于常模(平均100分)(认知平均为96.5，语言平均为93.8，运动平均为94.0，均为P<；0.03)。与寄养/领养家庭一起生活的儿童在随访时的认知得分(中位数100比95，p=0.03)比那些与亲生亲属一起生活的孩子高，而且运动能力得分和85分的可能性较小(p=0.02)。8%的儿童需要治疗斜视。接受NAS治疗的儿童在2岁时比普通人群有较低的发育评分和较高的斜视率的风险。
Little is known about developmental outcomes in neonatal abstinence syndrome (NAS). We hypothesized that children treated for NAS would score lower than the normative sample on the Bayley Scales of Infant Development, 3rd edition. We performed a retrospective cohort study of 87 infants treated for NAS and evaluated at 2 years of age. Children treated for NAS scored significantly lower than the norm (mean 100) on all 3 subscales (cognitive mean 96.5, language mean 93.8, motor mean 94.0, all p<0.03). Children who lived with foster/adoptive families at follow up had higher cognitive scores (median 100 vs 95, p=0.03) than those who lived with biological relatives, and were less likely to have motor scores <85 (p = 0.02). Eight percent of children required treatment for strabismus. Children treated for NAS are at risk for lower developmental scores and higher rates of strabismus at age 2 than the general population.
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影响因子：
2.9
作者：
Vestal-Laborde AA;Eschenroeder AC;Bigbee JW;Robinson SE;Sato-Bigbee C
通讯作者：
Sato-Bigbee C
影响因子：
3.6
作者：
Luine, Victoria;Gomez, Juan;Beck, Kevin;Bowman, Rachel
通讯作者：
Bowman, Rachel
影响因子：
120.7
作者：
Patrick, Stephen W.;Schumacher, Robert E.;Davis, Matthew M.
通讯作者：
Davis, Matthew M.
影响因子：
4.1
作者：
McGlone, Laura;Hamilton, Ruth;Mactier, Helen
通讯作者：
Mactier, Helen
影响因子：
3.5
作者：
Ornoy, A
通讯作者：
Ornoy, A